Bos taurus (A-2) urine assisted bioactive cobalt oxide anchored ZnO: a novel nanoscale approach

Abstract

In this study, a novel synthetic method for cobalt oxide (Co3O4) nanoparticles using Bos taurus (A-2) urine as a reducing agent was developed. In addition to this ZnO nanorods were produced hydrothermally and a nanocomposite is formed through a solid-state reaction. The synthesized materials were characterized through modern characterization techniques such as XRD, FE-SEM with EDS, DLS, zeta potential, FT-IR, Raman spectroscopic analysis, and TGA with DSC. The free radical destructive activity was determined using two different methods viz. ABTS and DPPH. The potential for BSA denaturation in vitro, which is measured in comparison to heat-induced denaturation of egg albumin and results in anti-inflammatory effects of nanomaterial was studied. All synthesized nanomaterials have excellent antibacterial properties, particularly against Salmonella typhi and Staphylococcus aureus. The composite exhibits excellent antioxidant and anti-inflammatory activities in comparison to pure nanomaterials. This reveals that these nanomaterials are advantageous in medicine and drug administration.

Chemical Composition Antioxidant and Anti-Inflammatory Activities of Myrtus communis L. Leaf Extract: Forecasting ADMET Profiling and Anti-Inflammatory Targets Using Molecular Docking Tools

“…Chronic inflammation has been closely associated with tumor progression [ 71 ]. Denaturation causes changes in the physiochemical properties of protein, which can be caused by inflammatory agents [ 72 ]. Some external factors, including stress and chemicals, can induce denaturation, leading to the loss of the highly ordered quaternary, tertiary, and secondary structures and the breakage of many weak bonds, including hydrogen bonds responsible for the native structure of protein; this is one of the significant characteristics of inflammation.…”

Bio-synthesized ZnO nanoparticles and sunlight-driven photocatalysis for environmentally-friendly and sustainable route of synthetic petroleum refinery wastewater treatment

“…Presently, a variety of semiconductor-based nanophotocatalysts have been applied in water pollution remediation, with a significant emphasis on metal oxide nanoparticles 10 – 12 . Notably, zinc oxide (ZnO) has garnered considerable attention in this regard.…”