Botulinum toxin: Bio Warfare Agent and Vaccine Development

Sharma, A.

doi:10.15761/crt.1000348

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2024

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Cited by 3 publications

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Tobacco as green bioreactor for therapeutic protein production: latest breakthroughs and optimization strategies

Naeem,

Han,

Ahmad

et al. 2023

Plant Growth Regul

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Tobacco as green bioreactor for therapeutic protein production: latest breakthroughs and optimization strategies

Naeem,

Han,

Ahmad

et al. 2023

Plant Growth Regul

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Botulism

Nikiforov

2024

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The monograph discusses etiology, epidemiology, pathogenesis, clinical course, treatment, diagnosis, differential diagnosis and prevention of botulism. The pathogenesis of botulism is presented in the light of current data, in connection with which the expediency of various therapeutic measures is critically reconsidered. Much attention is paid to the description of intensive care of patients with severe forms of botulism using assisted ventilation and nasotracheal intubation, as well as the causes of the most typical complications and measures for their prevention and elimination. The clinical picture is described considering the form of the disease — food, wound botulism and botulism in infants. A separate chapter is devoted to the use of botulinum neurotoxin for therapeutic and cosmetic (aesthetic) purposes, as well as possible side effects of botulinum therapy (iatrogenic botulism).

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Botulinum neurotoxin is both poison and medicine: botulinum therapy and iatrogenic botulism

Nikiforov

2023

Epidemiology and Infectious Diseases

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Botulinum neurotoxin (BnT) is the most potent of all the poisons known to the world. Over the past two centuries, its structure and functions have been studied in detail, it is obtained in its pure form. Knowledge of the mechanisms of action of BnT has determined two directions of its possible use: negative, as a biological (toxin) weapon, and positive - as a drug that eliminates pathological muscle hypertonicity, neuropathic pain and can be used for aesthetic purposes ("beauty injections"). The lecture gives a chronology of the development of both directions and a detailed analysis of the medical use of BnT both therapeutically and cosmetically. Particular attention is paid to the side effects of botulinum therapy and ways to overcome them.

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Botulinum toxin: Bio Warfare Agent and Vaccine Development

Cited by 3 publications

References 23 publications

Tobacco as green bioreactor for therapeutic protein production: latest breakthroughs and optimization strategies

Tobacco as green bioreactor for therapeutic protein production: latest breakthroughs and optimization strategies

Botulism

Botulinum neurotoxin is both poison and medicine: botulinum therapy and iatrogenic botulism

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