Botulinum toxin for scars: Can it work, does it work, is it worth it?

Freshwater, M. Felix

doi:10.1016/j.bjps.2012.11.034

Cited by 12 publications

(8 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, controversy is served [93,94], and larger, randomized, controlled studies need to be conducted to test the effect of chemoimmobilization in scarring [95]. …”

Section: Classical Treatment and Preventive Options For Keloids Anmentioning

confidence: 99%

“…However, recent research proposes that both types of excessive scarring show parallel and separated collagen fibers, in opposed to normal skin (with higher distance between collagen bundles in keloids) [93]. Actually, histomorphology of each scar not only differs from patient to patient, but also among scars from the same patient and among areas of the same scar [94], complicating even more the differential diagnosis.…”

Section: Figurementioning

confidence: 99%

See 1 more Smart Citation

Up-to-date approach to manage keloids and hypertrophic scars: A useful guide

Arno

Gauglitz

Barret

et al. 2014

Burns

312

314

View full text Add to dashboard Cite

Keloids and hypertrophic scars occur anywhere from 30 to 90% of patients, and are characterized by pathologically excessive dermal fibrosis and aberrant wound healing. Both entities have different clinical and histochemical characteristics, and unfortunately still represent a great challenge for clinicians due to lack of efficacious treatments. Current advances in molecular biology and genetics reveal new preventive and therapeutical options which represent a hope to manage this highly prevalent, chronic and disabling problem, with long-term beneficial outcomes and improvement of quality of life. While we wait for these translational clinical products to be marketed, however, it is imperative to know the basics of the currently existing wide array of strategies to deal with excessive scars: from the classical corticotherapy, to the most recent botulinum toxin and lasers. The main aim of this review paper is to offer a useful up-to-date guideline to prevent and treat keloids and hypertrophic scars.

show abstract

“…However, controversy is served [93,94], and larger, randomized, controlled studies need to be conducted to test the effect of chemoimmobilization in scarring [95]. …”

Section: Classical Treatment and Preventive Options For Keloids Anmentioning

confidence: 99%

Section: Figurementioning

confidence: 99%

Up-to-date approach to manage keloids and hypertrophic scars: A useful guide

Arno

Gauglitz

Barret

et al. 2014

Burns

312

314

View full text Add to dashboard Cite

show abstract

“…In both cases, use of the treatment does not occur in isolation but rather as a complementary therapy. Still, further studies are necessary (91,92). …”

Section: Introductionmentioning

confidence: 99%

Update on hypertrophic scar treatment

Rabello¹,

Souza²,

Júnior³

2014

Clinics

217

148

View full text Add to dashboard Cite

Scar formation is a consequence of the wound healing process that occurs when body tissues are damaged by a physical injury. Hypertrophic scars and keloids are pathological scars resulting from abnormal responses to trauma and can be itchy and painful, causing serious functional and cosmetic disability. The current review will focus on the definition of hypertrophic scars, distinguishing them from keloids and on the various methods for treating hypertrophic scarring that have been described in the literature, including treatments with clearly proven efficiency and therapies with doubtful benefits. Numerous methods have been described for the treatment of abnormal scars, but to date, the optimal treatment method has not been established. This review will explore the differences between different types of nonsurgical management of hypertrophic scars, focusing on the indications, uses, mechanisms of action, associations and efficacies of the following therapies: silicone, pressure garments, onion extract, intralesional corticoid injections and bleomycin.

show abstract

“…Die Idee, Botulinumtoxin bei frischen Wunden im Gesichtsbereich (traumatisch oder chirurgisch) anzuwenden, beruht auf der Vorstellung, dass durch Ruhigstellung der Wundränder eine bessere Wundheilung im Sinne von weniger ausgeprägter Narbenbildung ermöglicht wird. Bisher konnte sich diese Therapie allerdings nicht wirklich durchsetzen, da Studien zeigten, dass nur Experten die Wunden als besser beurteilten, von Patienten jedoch kein Unterschied festgestellt werden konnte [11][12][13] [17]. Die Behandlung der chronischen Migräne muss daher immer in ein therapeutisches Gesamtkonzept eingebunden sein.…”

Section: Traumatische Und Chirurgische Gesichtswundenunclassified

Botulinumtoxintherapie – neue Entwicklungen in der Augenheilkunde

Wabbels

2017

Klin Monatsbl Augenheilkd

View full text Add to dashboard Cite

Botulinum toxin is recognised as the gold standard for the treatment of essential blepharospasm and hemifacial spasm, which is similar in effect in synkinesis after facial nerve palsy. The injection intervals can be adjusted according to the patients' needs and be shortened for up to six weeks in cases of eyelid cramping. Newer indications for the use of botulinum toxin in ophthalmology include eyelid retraction in Graves' disease, induction of protective ptosis and treatment of crocodile tears syndrome after facial nerve palsy. In future, botulinum toxin may be used in depression (facial feedback), facial injuries and for protection of facial glands against irradiation injury.

show abstract

Botulinum toxin for scars: Can it work, does it work, is it worth it?

Cited by 12 publications

References 6 publications

Up-to-date approach to manage keloids and hypertrophic scars: A useful guide

Up-to-date approach to manage keloids and hypertrophic scars: A useful guide

Update on hypertrophic scar treatment

Botulinumtoxintherapie – neue Entwicklungen in der Augenheilkunde

Contact Info

Product

Resources

About