Brain abscess and epidural empyema caused by Salmonella enteritidis in a child: successful treatment with ciprofloxacin: a case report

Intracranial abscesses are life-threatening infections that pose a diagnostic challenge not only to the neurosurgeon but also to the microbiologists. Detailed studies documenting the spectrum of infecting agents involved in brain abscesses are limited from India. Materials and Methods. This is a retrospective analysis of 352 samples from 1987 to 2010 analyzed at a tertiary care hospital in South India from 1987 to 2010, to document the changing trends with time. Results. The age of the patients ranged from 2 to 80 years, a larger number of males being affected. Otogenic infections were the most common cause while cryptogenic abscesses were 20%. Gram stain and culture positivity were 78% each. Gram-positive and negative facultative aerobes and obligate anaerobes were also on the rise. Unusual organisms, like Burkholderia pseudomallei, Salmonella typhi, Nocardia species, Cladosporium bantiana, Fonsecaea pedrosoi, Entamoeba histolytica, and Acanthamoeba were also isolated and/or detected from the brain abscesses aspirate or resected tissue. Summary. New and emerging pathogens associated with brain abscess, especially in immunosuppressed individuals, have renewed the necessity of an early detection, and it will be of great value in appropriate management of patients with brain abscess.

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“…Salmonella typhi is a rare pathogen in brain abscess and probably spreads to the brain hematogenously [40]. …”

Section: Culture For Various Organismsmentioning

confidence: 99%

Microbiological Spectrum of Brain Abscess at a Tertiary Care Hospital in South India: 24-Year Data and Review

Lakshmi

Umabala

Anuradha

et al. 2011

Pathology Research International

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“…[137212628–30] Table 1 lists the details of the reported cases, treatments and outcomes. Intracranial Salmonella infections were most frequently associated with glioblastoma (6 cases), craniopharyngioma (2 cases), and ependymoma, (1 case).…”

Section: Discussionmentioning

confidence: 99%

“…[1924] Uncommon presentations like, subdural and epidural abscesses have also been reported. [11924] Brain abscess are more often seen in adults; whereas, meningitis and subdural empyema present more often in children, especially in infants. [1924] The predisposing factors for intracranial Salmonella include primary or metastatic brain tumors, areas of old ischemia or infarction, subarachnoid hemorrhage, epidural or subdural hematoma, and immunodeficiency.…”

Section: Discussionmentioning

confidence: 99%

“…[1924] The predisposing factors for intracranial Salmonella include primary or metastatic brain tumors, areas of old ischemia or infarction, subarachnoid hemorrhage, epidural or subdural hematoma, and immunodeficiency. [137141921242628–30] Clinical presentations of brain abscess due to Salmonella have been divided into three groups: 1) brain abscess formation during Salmonella infection elsewhere in the body;[1] 2) abscess formation after recovery from Salmonella infection;[10] 3) abscess formation in patients without any previous history of Salmonella. [26] Our case belongs to this third group, where Salmonella infection was not even suspected.…”

Section: Discussionmentioning

confidence: 99%

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Rare case of intracranial Salmonella enteritidis abscess following glioblastoma resection: Case report and review of the literature

Sait

Rahmathulla²,

Chen³

et al. 2011

Surg Neurol Int

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Background:Worldwide, Salmonella enteritidis (SE) is becoming a common cause of gastrointestinal infections by contaminated food products, mainly eggs. Extra-intestinal manifestations such as brain abscess are more commonly associated with Salmonella typhimurium and are rare in adults. We report the clinical features, treatment outcomes and risk factors predisposing our patient to Salmonella enteritidis brain abscess and discuss relevant literature.Case Description:A 57-year-old-man developed SE subdural empyema, abscess and possible ventriculitis following reoperation for progression of a right temporal glioblastoma. He initially presented with rapidly worsening headaches over a few days, with a wound discharge and associated meningeal signs. An emergent wound washout revealed pus in the epidural, subdural space and resection cavity. An external ventricular drain (EVD) was placed and cultures revealed gram negative rods. Timely intervention, EVD, and antibiotics resulted in complete resolution. Nine cases of Salmonella abscess associated with primary brain tumor have been reported in literature, most frequently caused by SE in association with glioblastoma multiforme (GBM). We describe our management and outcome in addition to discussing neurosurgical literature on the reported cases.Conclusions:Re-operative tumor surgery has a higher incidence of post-operative infections, with Gram positive cocci being the most common pathogens. Predisposing factors reported for intracranial salmonellosis include compromised immunity, diabetes, HIV, and recent travel. Chronic corticosteroid use, multiple regimens of chemotherapy, and regions of tumor necrosis likely potentiate this rare infection in GBM patients.

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“…The swelling measured around 5 cm × 5 cm. [16,17] In most of these cases of abscesses due to S. Enteritidis, patients have some underlying malignancy. Tenderness was associated with the swelling.…”

Section: Case Reportmentioning

confidence: 99%

Unusual manifestation of salmonella enterica serotype enteritidis infection in a case of langerhans cell histiocytosis

Praharaj

Sujatha

et al. 2013

Indian Journal of Medical Microbiology

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Nontyphoidal Salmonella (NTS) are established foodborne pathogens, most commonly reported in cases of gastroenteritis. These pathogens are however, increasingly being implicated in cases of bacteraemia and other extraintestinal manifestations. We report a case of a scalp abscess due to Salmonella enterica serotype Enteritidis, which is a serotype of NTS, in a child suffering from a haematologic malignancy. The child was on steroid and anticancer chemotherapy and developed the abscess secondary to bacteraemia with Salmonella Enteritidis. The abscess was drained and resolved following a course of intravenous antibiotic treatment.

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Brain abscess and epidural empyema caused by Salmonella enteritidis in a child: successful treatment with ciprofloxacin: a case report

Cited by 4 publications

References 1 publication

Microbiological Spectrum of Brain Abscess at a Tertiary Care Hospital in South India: 24-Year Data and Review

Microbiological Spectrum of Brain Abscess at a Tertiary Care Hospital in South India: 24-Year Data and Review

Rare case of intracranial Salmonella enteritidis abscess following glioblastoma resection: Case report and review of the literature

Unusual manifestation of salmonella enterica serotype enteritidis infection in a case of langerhans cell histiocytosis

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