“…A wide range of neuropathological findings were reported, including: hydrancephaly, anencephaly, holoprosencephaly, cerebral dysgenesis, abnormal neural migration, hydrocephaly, microcephaly/microencephaly, enlarged/reduced/ absent ventricles, and severe CNS disorganization. Furthermore, abnormalities of the basal ganglia, diencephalon, cerebellum, brainstem, optic nerve, olfactory bulb, hippocampus, pituitary, and neural tube were reported (Clarren, 1986;Clarren et al, 1978;Coulter et al, 1993;Jones and Smith, 1975;Peiffer et al, 1979;Wisniewski et al, 1983). Such heterogeneous brain malformations led to the conclusion that no identifiable pattern of brain abnormalities specific to FAS existed (Clarren et al, 1978;Peiffer et al, 1979).…”