1990
DOI: 10.1001/archsurg.1990.01410140044008
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Breast Biopsy for Calcifications in Nonpalpable Breast Lesions

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Cited by 18 publications
(12 citation statements)
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“…Rather than upholding the validity of concerns for over-diagnosis of an indolent process, our findings support the view that the assessment of microcalcifications leads to the detection of a significant number of biologically significant invasive cancers and preferentially detects higher grades of DCIS (Franceschi et al , 1990; Evans and Blanks, 2002; Stomper et al , 2003; Kuzmiak et al , 2006). …”
Section: Discussionsupporting
confidence: 50%
“…Rather than upholding the validity of concerns for over-diagnosis of an indolent process, our findings support the view that the assessment of microcalcifications leads to the detection of a significant number of biologically significant invasive cancers and preferentially detects higher grades of DCIS (Franceschi et al , 1990; Evans and Blanks, 2002; Stomper et al , 2003; Kuzmiak et al , 2006). …”
Section: Discussionsupporting
confidence: 50%
“…Its true incidence in the general population therefore cannot be reliably determined and is probably underestimated [8, 50, 54--56]. The results of 18 series [58][59][60][61][62][63][64][65][66][67][68][69] that reported 6609 nonpalpable breast biopsies (Table 2) show LCIS to comprise 2.2% (143 of 6609) of all biopsy specimens and 9.8% (143 of 1455) of all breast malignancies [31]. The results of 18 series [58][59][60][61][62][63][64][65][66][67][68][69] that reported 6609 nonpalpable breast biopsies (Table 2) show LCIS to comprise 2.2% (143 of 6609) of all biopsy specimens and 9.8% (143 of 1455) of all breast malignancies [31].…”
Section: Lcismentioning
confidence: 99%
“…These cells are well differentiated with no mitoses or atypical or pleomorphic features. Calcium is generally deposited in these necrotic areas, giving rise to the most common mammographic manifestation of DCIS [60,62,105,108]. As this cellular proliferation continues, the ductal lumen becomes filled until only scattered, rounded spaces remain interspersed among sheets of more atypical cells, known as the cribriform pattern of DCIS [8].…”
Section: Dcismentioning
confidence: 99%
“…Some 15–20% of these lesions are malignant, and their removal should be preceded by a radiographically guided localization procedure to assure an accurate and low tissue volume biopsy 4,5. Several techniques have been developed as a diagnostic and therapeutic tool.…”
Section: Introductionmentioning
confidence: 99%