Breast cancer and DDT: putative interactions, associated gene alterations, and molecular pathways

2021

JPRI

Aim: The study aims to analyze the specific gravity with the hemoglobin of the blood. Introduction: The ratio of the density of a substance to the density of the water at a specified temperature and pressure is known as specific gravity. Blood is a fluid connective tissue that delivers oxygen and nutrients to the cells and transports metabolic waste away from the cells. Red blood cells are biconcave disc-shaped cells produced from bone marrow. It contains proteins that transport oxygen from the lungs to all the parts of the body. The term heme reforms to the iron-containing porphyrin. The aim of the study was to analyse the specific gravity of Hemoglobin of the blood. Materials and Methods: 10 random blood samples were collected from the patients in Saveetha Dental College. Then the samples were centrifuged and the blood-specific gravity and hemoglobin were analyzed from the sample using a multi-reagent strip and the specific gravity and hemoglobin was determined. Results and Discussion: The mean specific gravity value of age group 21 - 30 years is 1.015, the mean specific gravity value of age group 31 - 40 years is 1.018, the mean specific gravity value of age group 41 - 50 is 1.016, and the mean specific gravity value of age group more than 50 years is 1.020. The mean specific gravity value of females is 1.01750 and the mean specific gravity value of males is 1.01750. The mean Hb value of females is 11.67 and the mean Hb value of males is 14.68. Conclusion: The value of mean specific gravity is slightly increased among different age groups and the mean Hb value is also slightly increased with different age groups. Between genders mean specific gravity is equal to both genders and mean Hb value is more in males compared with females.

Section: Resultsmentioning

confidence: 99%

Comparative Analysis of Specific Gravity with Hemoglobin of the Blood - Clinicopathological Analysis

Surya

Sinduja

2021

JPRI

“…The futurescope of the study, we have planned to inject a drug (Ketamine hydrochloride with saline) into the rat and absorb the layers of the cerebral cortex and hippocampus. Our team has extensive knowledge and research experience that has translated into high quality publications [21,[22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40].…”

Section: Discussionmentioning

confidence: 99%

Analysis of Histological Features of the Cerebral Cortex and Hippocampus of Albino Rats Using Haematoxylin & Eosin Stain- An Observational Study

Shreejha

Sinduja

et al. 2021

JPRI

Background: The study determined the histological layers of the cerebral cortex and hippocampus of the albino rat brain samples has been used in the study. The Cerebral cortex is composed of the Molecular layer, external granular, external pyramidal layer, internal granular layer and interior pyramidal layer. The layers of the hippocampus are alveus, stratum oriens, stratum pyramidale, stratum radiatum, stratum lacunosum and stratum moleculare. The aim of the study is to analyze the detailed histological features of the cerebral cortex and hippocampus layers of albino rats at the magnification of 10X,100X,40X. By using haematoxylin and eosin stain as an observational study. Materials and Methods: The samples were preserved and fixed with the formalin and stained by haematoxylin and eosin and observed with a light microscope. Results: The molecular layer is the superficial layer containing neurons. The outer granular layer of the cells are densely packed. Outer pyramidal layer contains rich pyramidal cells, Inner granular layer contains stellate cells, Inner pyramidal layer contains glial cells and the deeper multiform layer is composed of pyramidal cells. The hippocampus contains three layers of cornu Ammonia CA1, CA2, CA3. CA1 responds to memory and is covered by the choroid plexus. CA2 contains 3 major cell dentate gyrus, pyramidal cells, pyramidal neurons and CA3 composed of stratum lucidum. Conclusion: The study of brain analysis of histological features of the cerebral cortex and hippocampus of the brain adds a greater insight in understanding the histology of various types of layers in rat brain and morphology of brain cells.

“…Treatment choices are limited, and commonly involves lifelong immunoglobulin replacement therapy [5,6]. The most common systemic immunodeficiency disorders are HIV, anemia, diabetes mellitus, chemotherapy-induced immunodeficiency disorders [7][8][9][10].…”

Section: Mini-review Articlementioning

confidence: 99%

Mechanism of Common Systemic Immunodeficiency Disorders and its Literature Comparison

Ruskin

Sindhuja

2021

JPRI

Systemic immunodeficiency disorders are heterogenous groups ofImmunodeficiency disorders could experience an assortment of clinical signs, including intermittent, extreme, or irregular diseases, autoimmunity, and lymphoproliferative/malignancies. Immunodeficiency involves an enormous amount of sicknesses, influencing the advancement of the immune system, its function, or both. There is a increase in percentage of immunodeficiency disorders among population. However, numerous patients are diagnosed late; numerous cases experience the ill effects of difficulties by chronic infections, end-organ damage, or even demise before the diagnosis is made. Ideal determination and suitable treatment remain key to the successful management of patients. The objective of this review is to overview the various systemic immunodeficiency disorders and their mechanism of occurrence of immunodeficiency.