2006
DOI: 10.1111/j.1524-4741.2006.00342.x
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Breast Cancer-Related Lymphedema ? What Are the Significant Predictors and How They Affect the Severity of Lymphedema?

Abstract: According to the American Cancer Society, there are currently 2 million breast cancer (BC) survivors in the USA and 20% of them cope with lymphedema (LE). The primary aim of this study was to determine the predictive factors of BC-related LE. The secondary aim was to investigate the impact of predictors on the severity of LE. The study design was intended to be a 1:2 matched case-control study. Instead, we stratified on age (+/-10 years), radiation therapy (y/n), and type of operation (SM/MRM/MRM with tram). P… Show more

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Cited by 151 publications
(143 citation statements)
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References 49 publications
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“…Dissecção de linfonodo axilar, RT. Soran et al 2 Caso controle 104 pacientes no grupo controle sem linfedema e 52 mulheres com linfedema.…”
Section: Dados Do Artigounclassified
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“…Dissecção de linfonodo axilar, RT. Soran et al 2 Caso controle 104 pacientes no grupo controle sem linfedema e 52 mulheres com linfedema.…”
Section: Dados Do Artigounclassified
“…de dissecção axilar Herd-Smith et al 16 A RT promoveria a formação de fibrose tecidual, com consequente vasoconstrição linfática, significativo prejuízo à função de filtração do linfonodo e alteração da resposta imunológica. Soran et al 2 A formação de anastomoses linfo-linfáticas previnem o linfedema e, mesmo sem sintoma clínico, a disfunção linfática está presente na maioria das pacientes no P.O. câncer de mama.…”
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“…Disease related factors include tumor stage at time of diagnosis, pathologic nodal status, number of removed lymph nodes, and the location of the tumor in the breast [8,9]. Patient related factors include age at diagnosis, high body mass index (BMI), hypertension, history of infection or inflammation, hand dominance, and excessive use of the affected limb [1,[10][11][12].…”
Section: Introductionmentioning
confidence: 99%