Breast cancer with low FDG uptake: characterization by means of dual-time-point FDG-PET/CT

Diagnostic accuracy of dual-time-point 18F-FDG PET/CT for the detection of axillary lymph node metastases in breast cancer patients

“…Analogously to primary breast cancer lesions (12,13,22) there is an increase of the SUVmax of axillary lymph node metastases when comparing measurements at time points T1 and T2 60 and 90 min after FDG injectioneven marginal in this study. This, however, did not translate into an improvement of the diagnostic accuracy of FDG-PET/CT for the detection of axillary lymph node metastases.…”

SUV on Dual-Phase FDG PET/CT Correlates With the Ki-67 Proliferation Index in Patients With Newly Diagnosed Non-Hodgkin Lymphoma

“…Because of this different time course in FDG uptake between malignant and inflammatory cells, a delayed PET scan is expected to show a higher lesion-to-background ratio, differentiate inflammation from malignancy more precisely, and thus improve diagnostic accuracy. Dual-phase FDG PET/CT has been reported to result in higher sensitivity and specificity for the diagnosis of esophageal cancer, 44 pulmonary nodules, 45,46 breast cancer, 47,48 cervical cancer, 49 and hepatic lesions. 50 In addition, it can provide diagnostic value especially for evaluation of lymph nodes metastasis in esophageal cancer, 44 cervical cancer, 51 and nonYsmall cell lung cancer.…”

Dual-time-point Imaging and Delayed-time-point Fluorodeoxyglucose-PET/Computed Tomography Imaging in Various Clinical Settings

“…24,54,55 Several studies have investigated the applicability of DTPI for improvement of the results from FDG-PET/CT for diagnosis, assessment of axillary lymph nodes, and recurrence of breast cancer. 24,25,[56][57][58][59] Mavi and colleagues 24 in a study of 152 patients with DTPI observed an increase in the uptake of FDG at the second time point in patients with malignant breast lesions. They also noted differences in the increase of FDG uptake, which might reflect the tumor biology.…”