Breast Tumor as the Presenting Sign of Multiple Myeloma

Breast Myeloma

“…[1][2][3][4][5][6][7][8][9][10] They may present as an extramedullary form or in association with multiple myeloma. The cytologic findings of breast plasmacytoma have been rarely reported.…”

Bilateral Plasmacytoma of the Breast: A Case Report

“…Such lesions have been found most commonly in the upper respiratory tract, but have also been reported in the lung, gastrointestinal tract, lymph nodes, and skin (2). Plasmacytoma of the breast is rare, however, with only 12 cases reported to date (3–12).…”

Plasmacytoma of the Breast

“…In the majority of cases, patients ultimately develop evidence of multiple myeloma. 2 Some cases show a synchronous diagnosis of multiple myeloma with workup of the breast lesion, 3,6,7,11 while others have development of the breast lesion prior 5 to or following 2,4,9 the diagnosis of multiple myeloma. An unusual presentation is the recurrence of disease by development of a breast mass in patients with chemotherapy-responsive multiple myeloma who are clinically in remission.…”

“…Extraskeletal spread of plasma cell myeloma is common at autopsy 1 ; however, clinical involvement of the breast is distinctly unusual, with few cases reported. [2][3][4][5][6][7][8][9][10][11] The occurrence of a solitary extramedullary plasmacytoma of the breast without systemic evidence of myeloma is also quite unusual. [12][13][14][15][16] We describe two patients with plasma cell neoplasms of the breast diagnosed by fine needle aspiration biopsy, which enabled a reliable, rapid and cost-effective method of diagnosis, avoiding open surgical biopsy.…”