2019
DOI: 10.1080/14786419.2018.1534850
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Briarane-type diterpenoids from the Vietnamese gorgonian Junceella fragilis

Abstract: Ten briarane-type diterpenoids (1−10), including one new stereoisomer 17-epijunceellolide B (1), were isolated from the MeOH extract of the Vietnamese gorgonian Junceella fragilis. Their structures were elucidated by spectroscopic experiments including 1D and 2D NMR, and HR-QTOF-MS. In addition, the in vitro cytotoxic activity against eight human cancer cell lines (LNCaP, HepG2, KB, MCF-7, SK-Mel2, HL-60, LU-1 and SW480) of all isolated compounds were evaluated by SRB assays.

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Cited by 7 publications
(1 citation statement)
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“…A Vietnamese sample of the gorgonian Junceella fragilis contains the new 17- epi -junceellolide B ( 105 ), along with nine known briarane diterpenoids . Samples of Briareum excavatum , both laboratory cultured , and isolated from a Taiwanese sample, yielded the four new chlorine-containing briaranes, briarenols M ( 106 ) and N ( 107 ), P ( 108 ), and L ( 109 ) .…”
Section: Coralsmentioning
confidence: 99%
“…A Vietnamese sample of the gorgonian Junceella fragilis contains the new 17- epi -junceellolide B ( 105 ), along with nine known briarane diterpenoids . Samples of Briareum excavatum , both laboratory cultured , and isolated from a Taiwanese sample, yielded the four new chlorine-containing briaranes, briarenols M ( 106 ) and N ( 107 ), P ( 108 ), and L ( 109 ) .…”
Section: Coralsmentioning
confidence: 99%