There is increasing recognition that an entrepreneurial philanthropy partnership (EPP) has become a modus operandi for non-profit organisations and for-profit companies, aligning their interactions according to societal expectations. While these partnerships offer many advantages in principle, there is little consensus by academics and practitioners on what it presents for action, and its practice varies. The purpose of this article is to address the characteristics of EPPs that are associated with its establishment and with maintaining the continuous dialogue of tacit and explicit know-how. Therefore, a theoretical Entrepreneurial Philanthropy Alignment Model has been developed and is empirically tested in the context of existing EPPs in The Netherlands. The model may inform continuing theory building and practical experimentation to refine defining the amplitude of partnership practice, and to enhance the responsiveness to partners' expectations of an EPP.