Brief Outlook on Polymeric Nanoparticles, Micelles, Niosomes, Hydrogels and Liposomes: Preparative Methods and Action

Abstract

Polymeric nanoparticles, micelles, niosomes, hydrogels and liposomes represent effective drug carriers having huge potential for medical and pharmaceutical applications. These systems remain the most important area in medicinal chemistry research. The aforementioned biomaterials can effectively encapsulate and release diverse hydrophobic/hydrophilic therapeutic molecules including drugs and prodrugs. Applications of these carrier systems extend to nucleic acids, antibodies and proteins which could be released sustainably. Since these systems fall in the nano dimension, they are capable of enhancing the therapeutic efficacy of bioactive molecules besides enabling them to accumulate preferentially at the target site. Furthermore, these systems can protect the encapsulated drug from degradation, thereby increasing the therapeutic value of the drug candidate and reducing systemic toxicity. In this review, we illustrate the preparative methods and actions of these five drug delivery systems.

The strategic applications of natural polymer nanocomposites in food packaging and agriculture: Chances, challenges, and consumers’ perception

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Composition, preparation methods, and applications of nanoniosomes as codelivery systems: a review of emerging therapies with emphasis on cancer

“…While liposomes consist of phospholipid bilayers and micelles form singlelayered structures, nanoniosomes strike a balance between these, offering a versatile platform for targeted drug delivery, promising both stability and increased bioavailability. 45 Their innovative nature propels advancements in pharmaceuticals, offering a potential breakthrough in precision medicine and therapeutics. 46 Numerous advantages of niosomes, such as their capacity to transport multiple drugs at once and reduced systemic toxicity of the drugs in cancer treatments, have prompted researchers to use these nano-carriers for the codelivery of drugs.…”

“…While liposomes consist of phospholipid bilayers and micelles form single-layered structures, nanoniosomes strike a balance between these, offering a versatile platform for targeted drug delivery, promising both stability and increased bioavailability. 45 Their innovative nature propels advancements in pharmaceuticals, offering a potential breakthrough in precision medicine and therapeutics. 46…”

Preparation and Characterization of 5‐Fluorouracil Loaded Cellulose and Exosome Nanocarriers: Sustained Release Behavior and Cytotoxicity Studies**

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