Bringing IoT to the Lab: SiLA2 and Open-Source-Powered Gateway Module for Integrating Legacy Devices into the Digital Laboratory

Porr, Marc; Schwarz, Sebastian; Lange, F.; Niemeyer, Laura; Hentrop, Thorleif; Marquard, Daniel; Lindner, Patrick; Scheper, Thomas; Beutel, Sascha

doi:10.1016/j.ohx.2020.e00118

Cited by 14 publications

(25 citation statements)

References 12 publications

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“…All components are either based on open‐source software or have been previously described and released by the authors under an open‐hardware or open‐source license [12]…”

Section: Resultsmentioning

confidence: 99%

“…A lab manager can monitor the status of all connected devices and their gateways with a single web interface. The source code for this web interface was described before [12] and is publicly available under an open‐source license.…”

Section: Resultsmentioning

confidence: 99%

“…A gateway‐module was used to integrate such devices into the digitized lab network. The building and programming of this gateway module was described in detail by the authors before [12] and all plans and software are available under an open‐source or open‐hardware license. The module is part of the laboratory network and connects to the lab device via USB or serial/Recommended Standard 232.…”

Section: Methodsmentioning

confidence: 99%

“…In addition, deployment of these services is automated by a central publish‐system. Both the management and publish system, as well as a guide on how to write SILA2 translators as micro‐services, were published by the authors before [12] and are available under an open‐source license.…”

Section: Introductionmentioning

confidence: 99%

“…Devices that cannot be connected directly to the laboratory network, are integrated using a gateway module. This was described in detail by the authors before [12] and all necessary information and software are available under open licenses.…”

Section: Introductionmentioning

confidence: 99%

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Implementing a digital infrastructure for the lab using a central laboratory server and the SiLA2 communication standard

Porr

Lange

Marquard

et al. 2020

Engineering in Life Sciences

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In this report, a fully integrated solution for laboratory digitization is presented. The approach presents a flexible and complete integration method for the digitally assisted workflow. The worker in the laboratory performs procedures in direct interaction with the digitized infrastructure that guides through the process and aids while performing tasks. The digital transformation of the laboratory starts with standardized integration of both new and “smart” lab devices, as well as legacy devices through a hardware gateway module. The open source Standardization in Lab Automation 2 standard is used for device communication. A central lab server channels all device communication and keeps a database record of every measurement, task and result generated or used in the lab. It acts as a central entry point for process management. This backbone enables a process control system to guide the worker through the lab process and provide additional assistance, like results of automated calculations or safety information. The description of the infrastructure and architecture is followed by a practical example on how to implement a digitized workflow. This approach is highly useful for – but not limited to – the biotechnological laboratory and has the potential to increase productivity in both industry and research for example by enabling automated documentation.

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“…All components are either based on open‐source software or have been previously described and released by the authors under an open‐hardware or open‐source license [12]…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Implementing a digital infrastructure for the lab using a central laboratory server and the SiLA2 communication standard

Porr

Lange

Marquard

et al. 2020

Engineering in Life Sciences

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Digitale Zwillinge in der Bioprozesstechnik – Chancen und Möglichkeiten

Richter

Lange

Scheper

et al. 2022

Chemie Ingenieur Technik

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Herrn Prof. Dr. Christian Wandrey zum 80. Geburtstag gewidmet Die Digitalisierung von Prozessen ist eines der aktuell dominierenden Themen und Missionen sowohl in der industriellen Produktion als auch der wissenschaftlichen Forschung. In der Biotechnologie haben diese Bemu ¨hungen ein enormes Potenzial, um existierende Bioprozesse zu optimieren oder neue Bioprozesse fu ¨r zuku ¨nftige Herausforderungen zu entwickeln. In diesem U ¨bersichtsbeitrag wird der aktuelle Stand der Digitalisierung in der Bioprozesstechnik beleuchtet, die Begriffe digitaler Zwilling und digitaler Schatten charakterisiert sowie ein Ausblick auf zuku ¨nftige Lab 4.0-Konzepte gegeben.

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Digitalization concepts in academic bioprocess development

Habich,

Beutel

2024

Engineering in Life Sciences

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Digitalization with integrated devices, digital and physical assistants, automation, and simulation is setting a new direction for laboratory work. Even with complex research workflows, high staff turnover, and a limited budget some laboratories have already shown that digitalization is indeed possible. However, academic bioprocess laboratories often struggle to follow the trend of digitalization. Due to their diverse research circumstances, high variety of team composition, goals, and limitations the concepts are substantially different. Here, we will provide an overview on different aspects of digitalization and describe how academic laboratories successfully digitalized their working environment. The key aspect is the collaboration and communication between IT‐experts and scientific staff. The developed digital infrastructure is only useful if it supports the laboratory worker and does not complicate their work. Thereby, laboratory researchers have to collaborate closely with IT‐experts in order for a well‐developed and maintainable digitalization concept that fits their individual needs and level of complexity. This review may serve as a starting point or a collection of ideas for the transformation toward a digitalized laboratory.

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Bringing IoT to the Lab: SiLA2 and Open-Source-Powered Gateway Module for Integrating Legacy Devices into the Digital Laboratory

Cited by 14 publications

References 12 publications

Implementing a digital infrastructure for the lab using a central laboratory server and the SiLA2 communication standard

Implementing a digital infrastructure for the lab using a central laboratory server and the SiLA2 communication standard

Digitale Zwillinge in der Bioprozesstechnik – Chancen und Möglichkeiten

Digitalization concepts in academic bioprocess development

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