Broad spectrum bioactive sunscreens

Velasco, Maria Valéria Robles; Sarruf, Fernanda Daud; Salgado-Santos, Idalina Maria Nunes; Haroutiounian-Filho, Carlos Alberto; Kaneko, Telma Mary; Baby, André Rolim

doi:10.1016/j.ijpharm.2008.06.031

Cited by 120 publications

(101 citation statements)

References 35 publications

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“…Given the structural similarities between polyphenolic compounds and organic UV filters, in addition to the antioxidant activity of these bioactive compounds, they might exert photoprotective activity (Velasco et al, 2008a;Velasco et al, 2008b;Violante et al, 2009).…”

Section: Sun Protection Factor Study (Spf)mentioning

confidence: 99%

“…Other researchers (Dondi, Albini, Serpone, 2006;Velasco et al, 2008b) have reported that the association of UV filters with bioactive compounds in a complex medium, such as an emulsion, leads to a distinctive photochemical profile, different from the photochemistry of the isolated compounds.…”

Section: Sun Protection Factor Study (Spf)mentioning

confidence: 99%

“…According to Velasco et al (2008b) bioactive compounds interact with UV filters and their photoprotective efficacy may be dependent on the nature of the bioactive compound and UV filter concentrations.…”

Section: Sun Protection Factor Study (Spf)mentioning

confidence: 99%

“…The cited studies described the difficulty in increase in the SPF value by the addition of natural active agents in the formulation containing chemical and/or physical UV filters. When the P. incarnate L. dry extract interacted negatively with UV filters and led to reduction if the SPF value, Velasco et al (2008b) attributed this behavior to four main factors: presence of inorganic UV filter; composition of the vehicle; quantitative composition of the organic UV filter; and phytochemical composition of the extracts. These last three factors may explain why the açai glycolic extract failed to promote an the increase in the SPF value.…”

Section: Sun Protection Factor Study (Spf)mentioning

confidence: 99%

“…Other studies have been performed with the aim of increasing UVA protection using natural products (Rancan et al, 2002;Baby et al, 2008;Velasco et al, 2008b;Lohézic-Le Dévéhat et al, 2013).…”

Section: In Vitro Uva Protection Factor (Fp-uva) Determinationmentioning

confidence: 99%

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Development of O/W emulsions containing Euterpe oleracea extract and evaluation of photoprotective efficacy

Daher

Fontes

Rodrigues

et al. 2014

Braz. J. Pharm. Sci.

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Euterpe oleracea Mart. is a palm tree popularly known as açai, which is primarily found in northern Brazil. The açai's fruits contain anthocyanins, a class of polyphenols to which antioxidant properties have been attributed. The aim of this work was to develop O/W sunscreens emulsions containing açai glycolic extract (AGE) and to evaluate both their physical stability and photoprotective efficacy. Emulsions containing AGE and sunscreens were formulated using different types and concentrations of polymeric surfactant (acrylates/C 10-30 alkyl acrylate crosspolymer and sodium polyacrylate). The influence of two rheology modifiers (polyacrylamide (and) C13-14/isoparaffin (and) Laureth-7 and Carbomer) on the stability was also investigated. Physical stability was evaluated by preliminary and accelerated studies. Emulsions with 1.0% sodium polyacrylate were stable and exhibited non-newtonian pseudoplastic behavior and thixotropy. Photoprotective efficacy was evaluated by in vivo Sun Protection Factor (SPF) and determination of Protection Factor of UVA (PF-UVA). When AGE was added to the sunscreen emulsion, no significant increase in the in vivo SPF value was observed. The emulsion containing AGE showed PF-UVA = 14.97, 1.69 of the SPF/PF-UVA ratio and a critical wavelength value of 378 nm, and may therefore be considered a sunscreen with UVA and UVB protection. Euterpe oleracea Mart. é uma palmeira popularmente conhecida como açaí, encontrada no norte do Brasil. O fruto do açaí apresenta em sua composição antocianinas, uma classe de polifenóis à qual é atribuída propriedade antioxidante. Os objetivos desse trabalho foram desenvolver emulsões fotoprotetoras O/A contendo extrato glicólico de açaí (AGE), avaliar a estabilidade física e avaliar a eficácia fotoprotetora. Emulsões contendo AGE e filtros solares foram formuladas utilizando diferentes tipos e concentrações de tensoativo polimérico (acrilates/C 10-30 alquil acrilato polímero cruzado e polilacrilato sódico). A influência de dois modificadores reológicos (poliacrilamida (e) C13-14/isoparafina (e) Laureth-7 e Carbomer) na estabilidade foi avaliada. A estabilidade física das emulsões foi avaliada por meio de estudos de estabilidade preliminar e acelerada. Emulsões com 1,0% poliacrilato sódico foram estáveis, exibiram comportamento não-newtoniano pseudoplástico e tixotrópico. A eficácia fotoprotetora foi avaliada pelo teste in vivo de Fator de Proteção Solar (FPS) e pela determinação do Fator de Proteção UVA (FP-UVA). Quando adicionado o AGE na emulsão contendo filtros solares, não se observou aumento significativo no valor do FPS. A emulsão contendo o AGE apresentou FP-UVA=14,97, a razão FPS/ FP-UVA = 1,69 e o comprimento de onda crítico igual a 378 nm, podendo ser considerado um protetor solar com proteção UVA e UVB. Unitermos:Emulsão O/A/desenvolvimento. Euterpe oleracea/farmacognosia. Euterpe oleracea/extrato glicólico/eficácia fotoprotetora. Protetores Solares/desenvolvimento. Fator de Proteção Solar.

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Section: Sun Protection Factor Study (Spf)mentioning

confidence: 99%

Section: Sun Protection Factor Study (Spf)mentioning

confidence: 99%

Section: Sun Protection Factor Study (Spf)mentioning

confidence: 99%

Section: Sun Protection Factor Study (Spf)mentioning

confidence: 99%

Section: In Vitro Uva Protection Factor (Fp-uva) Determinationmentioning

confidence: 99%

See 3 more Smart Citations

Development of O/W emulsions containing Euterpe oleracea extract and evaluation of photoprotective efficacy

Daher

Fontes

Rodrigues

et al. 2014

Braz. J. Pharm. Sci.

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UV filters used in sunscreens—A lack in current coral protection?

Pawlowski

Moeller

Miller

et al. 2021

Integr Envir Assess & Manag

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Ultraviolet (UV) filters used in sunscreens are among the anthropogenic substances that may enter the marine environment by both indirect (via wastewater) and direct pathways (leisure activities). Owing to the recent global decline in coral population, the impact of those UV filters on the coral health is currently under increased investigation. First results from scientists suggest that some of the filters may be toxic to various coral life stages, but an initial cross comparison with existing data from other freshwater organisms does not indicate that corals are specifically more susceptible to UV filters than other standard species. In fact, the available data leading to this conclusion is still vague and based on toxicity and bioaccumulation tests with corals, which are both still at the research stage. To facilitate a proper hazard assessment, robust experimental procedures for coral ecotoxicological studies are considered mandatory. In other words, additional steps should be taken to standardize and validate such new test systems to generate reliable results, which then can be used in regulatory decision making. Furthermore, to facilitate a more detailed and site‐specific environmental risk assessment in the marine area, an application‐based exposure scenario must be developed. Until these data and tools become available, environmental hazard and risk assessments may be carried out using existing data from freshwater organisms and existing tonnage‐based exposure scenarios as a potential surrogate. Integr Environ Assess Manag 2021;17:926–939. © 2021 SETAC

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Sustainable Sunscreens: A Challenge Between Performance, Animal Testing Ban, and Human and Environmental Safety

Pawlowski

Petersen‐Thiery²

2020

The Handbook of Environmental Chemistry

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Broad spectrum bioactive sunscreens

Cited by 120 publications

References 35 publications

Development of O/W emulsions containing Euterpe oleracea extract and evaluation of photoprotective efficacy

Development of O/W emulsions containing Euterpe oleracea extract and evaluation of photoprotective efficacy

UV filters used in sunscreens—A lack in current coral protection?

Sustainable Sunscreens: A Challenge Between Performance, Animal Testing Ban, and Human and Environmental Safety

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