Bronchial hyperreactivity to inhaled histamine in patients with farmer’s lung

Mönkäre, S; Haahtela, Tari; Ikonen, M; Laitinen, Lauri A.

doi:10.1007/bf02713910

Cited by 25 publications

(9 citation statements)

References 12 publications

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“…However, bronchial symptoms such as wheezing and dry cough may be found in patients with HP. Bronchial hyper-responsiveness has been demonstrated during the acute phase of farmer's lung, or in subjects with past histories of the disease [12,13]. Our investigation con®rmed the existence of a working population strongly exposed to sausage mould, frequently immunized, with numerous symptoms, without functional consequences.…”

Section: Extractsupporting

confidence: 60%

Symptoms and serum precipitins in workers exposed to dry sausage mould: consequences of exposure to sausage mould

Rouzaud¹,

Soulat²,

Trela³

et al. 2001

International Archives of Occupational and Environmental Health

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Section: Extractsupporting

confidence: 60%

Symptoms and serum precipitins in workers exposed to dry sausage mould: consequences of exposure to sausage mould

Rouzaud¹,

Soulat²,

Trela³

et al. 2001

International Archives of Occupational and Environmental Health

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“…Nonspecific bronchial hyperresponsiveness [226,227] and wheezing may also be prevalent in subjects with recent hypersensitivity pneumonitis, especially in dairy farmers [228,229].…”

Section: Environmental or Occupational Exposurementioning

confidence: 99%

Small airways diseases, excluding asthma and COPD: an overview

Burgel¹,

Bergeron²,

Blic³

et al. 2013

Eur Respir Rev

105

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This review is the summary of a workshop on small airways disease, which took place in Porquerolles, France in November 2011. The purpose of this workshop was to review the evidence on small airways (bronchiolar) involvement under various pathophysiological circumstances, excluding asthma and chronic obstructive pulmonary disease. Histopathological patterns associated with small airways disease were reviewed, including cellular and obliterative bronchiolitis. Many pathophysiological conditions have been associated with small airways disease including airway infections, connective tissue diseases and inflammatory bowel diseases, bone marrow and lung transplantation, common variable immunodeficiency disorders, diffuse panbronchiolitis, and diseases related to environmental exposures to pollutants, allergens and drugs. Pathogenesis, clinical presentation, a computed tomography scan and pulmonary function test findings are reviewed, and therapeutic options are described with the objective of providing an integrative approach to these disorders.

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“…Airway hyperresponsiveness is a common finding in patients in the acute phase of farmers' lung. 12 13 At testing a few months later Mönkäre et al 12 found that in most of their cases there was no response to histamine as in our two patients.…”

Section: Humidifier Lungmentioning

confidence: 52%

Follow up investigation of workers in synthetic fibre plants with humidifier disease and work related asthma.

Pal¹,

Monchy²,

Groothoff³

et al. 1999

Occup Environ Med

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Objective-To investigate the clinical and sociomedical outcome in patients with various clinical manifestations of humidifier disease and work related asthma after removal from further exposure. Methods-Follow up investigation (range 1-13 years) of respiratory symptoms, spirometry, airway responsiveness, sickness absence, and working situation in patients with (I) humidifier fever (n=12), (II) obstructive type of humidifier lung (n=8), (III) restrictive type of humidifier lung (n=4), and (IV) work related asthma (n=22). All patients were working at departments in synthetic fibre plants with microbiological exposure from contaminated humidification systems or exposure to small particles (<1 µm) of oil mist.

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Bronchial hyperreactivity to inhaled histamine in patients with farmer’s lung

Cited by 25 publications

References 12 publications

Symptoms and serum precipitins in workers exposed to dry sausage mould: consequences of exposure to sausage mould

Symptoms and serum precipitins in workers exposed to dry sausage mould: consequences of exposure to sausage mould

Small airways diseases, excluding asthma and COPD: an overview

Follow up investigation of workers in synthetic fibre plants with humidifier disease and work related asthma.

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