Brucella Endocarditis in Prosthetic Valves

Mehanic, Snjezana; Mulabdic, Velida; Baljić, Rusmir; Hadzovic-Cengic, Meliha; Pinjo, Fikret; Hadžiosmanović, Vesna; Topalovic, Jasna

doi:10.5455/msm.2012.24.s11-s12

Cited by 6 publications

(16 citation statements)

References 10 publications

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“…In Bosnia, two IE case reports have been published, including one caused by Brucella melitensis [11] and one caused by Streptococcus pneumoniae in a 12-year-old child [12] . In addition, although no case of endocarditis has been reported in the scientific literature, Q fever is common in Bosnia, with 373 cases diagnosed between 1998 and 2003 [13] .…”

Section: Resultsmentioning

confidence: 99%

Endocarditis in the Mediterranean Basin

Gouriet¹,

Chaudet

Pellegrin

et al. 2018

New Microbes and New Infections

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Infective endocarditis is a severe disease with high mortality. Despite a global trend towards an increase in staphylococcal aetiologies, in older patients and a decrease in viridans streptococci, we have observed in recent studies great epidemiologic disparities between countries. In order to evaluate these differences among Mediterranean countries, we performed a PubMed search of infective endocarditis case series for each country. Data were available for 13 of the 18 Mediterranean countries. Despite great differences in diagnostic strategies, we could classify countries into three groups. In northern countries, patients are older (>50 years old), have a high rate of prosthetic valves or cardiac electronic implantable devices and the main causative agent is Staphylococcus aureus. In southern countries, patients are younger (<40 years old), rheumatic heart disease remains a major risk factor (45–93%), viridans streptococci are the main pathogens, zoonotic and arthropod-borne agents are frequent and blood culture–negative endocarditis remains highly prevalent. Eastern Mediterranean countries exhibit an intermediate situation: patients are 45 to 60 years old, the incidence of rheumatic heart disease ranges from 8% to 66%, viridans streptococci play a predominant role and zoonotic and arthropod-borne diseases, in particular brucellosis, are identified in up to 12% of cases.

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Section: Resultsmentioning

confidence: 99%

Endocarditis in the Mediterranean Basin

Gouriet¹,

Chaudet

Pellegrin

et al. 2018

New Microbes and New Infections

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“…Contact with infected animals and/or consumption of unpasteurized dairy milk has been reported in 26 patients (50.9%). Thirteen Patients (25.5%) were exposed by their profession or by their leisure activities: veterinarian in one patient [ 33 ], a stock-breeder in one patient [ 36 ], hunter in two patients [ 8 , 35 ], shepherd in five patients [ 8 , 27 , 30 , 31 ] and farmer in four patients [ 18 , 38 , 39 , 42 ] ( Table 1 ).…”

Section: Resultsmentioning

confidence: 99%

“…Most common type of prosthesis valve was mechanical prothesis (n = 43; 84.3%), eight (15.7%) patients had bioprosthetic valve [ 6 – 9 , 20 , 21 , 28 , 32 ], And ten patients (19.6%) had double valve prosthesis [ 5 , 18 , 19 , 23 , 29 , 31 , 32 , 36 , 39 ]. Prosthetic aortic valve involvement was reported in 27 patients (52.9%), prosthetic mitral valve involvement was reported in 18 patients (35.3%) and in two cases (3.9%) both the aortic and mitral prosthesis were affected [ 23 , 36 ]. No endocarditis in the tricuspid prosthesis valve was reported ( Table 2 ).…”

Section: Resultsmentioning

confidence: 99%

“…The mean duration of the symptoms before diagnosis was 3 ± 3 months (with extremes ranging from one week to 15 months). This duration was between two months and one year in ten patients [ 8 , 19 , 31 , 37 , 38 , 41 – 43 ], less or equal to two months in 24 patients [ 5 , 8 , 9 , 11 , 13 , 17 – 20 , 22 – 28 , 30 , 31 , 33 , 39 , 40 ] and above one year in four patients [ 6 , 15 , 35 , 36 ]. It was not specified for the rest of the patients.…”

Section: Resultsmentioning

confidence: 99%

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Brucella prosthetic valve endocarditis: a systematic review

Taamallah¹,

Hammami²,

Gharsallah³

et al. 2021

Journal of the Saudi Heart Association

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Objective Brucella prosthetic valve endocarditis is a rare but a life-threatening complication of brucellosis. It remains a diagnostic challenge. Optimal treatment of Brucella prosthetic valve endocarditis is debated. Available data is limited to case reports or small case series. The purpose of this study was to systematically review all published cases of Brucella prosthetic valve endocarditis in the literature. Method A systematic review of PubMed database, Google, Google Scholar, and Scopus (From January 1974 to the present) for studies providing epidemiological, clinical and microbiological data as well as data on treatment and outcomes of Brucella prosthetic valve endocarditis was performed. Results A total of 51 reported cases were reviewed. Brucella melitensis (45%) and Brucella abortus (11.7%) were the most frequently isolated species. Most common type of prosthesis valve was mechanical prothesis (84.3%) and ten patients had double valve prosthesis (19.6%). Fever and dyspnea were present in 100% and 37.2% of the cases, respectively. The diagnosis was set with echocardiographic finding in 30 cases (93.7%), which revealed vegetation in 27 cases (84.3%). Most used antibiotics were rifampicin, doxycycline and aminoglycoside or cotrimoxazole. No deaths were noted in patients treated by combined medical and surgical treatment, but mortality was noted in 27.7% of the cases treated by antibiotics alone (p = 0.006). Conclusion This systematic review highlights diagnostic challenges and demonstrates that surgery improved outcome by reducing mortality in patients treated with the combined surgical and medical treatment option. Brucellosis should be considered in the differential diagnosis of prosthetic valve endocarditis in patients residing in or traveling to areas of endemicity.

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“…Brucella endocarditis is a rare disease (2%–5 %) [ 1 ] affecting native, congenital, or prosthetic valve and associated with high mortality in 80 % of cases [ [1] , [2] , [3] , [4] ]. Brucella endocarditis on prosthetic valve is described in the literature [ 1 ], with an incidence of 8.3 % among all Brucella endocarditis cases [ 5 ]. In Saudi Arabia, Brucella is an etiology in 10 % of cases of prosthetic endocarditis [ 1 ].…”

Section: Discussionmentioning

confidence: 99%

Brucella prosthetic valve endocarditis with septic and cardiogenic shock

Hamieh

2020

IDCases

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A young man with aortic prosthetic valve replacement, presented with prolonged fever and diagnosed with brucella endocarditis based on positive transthoracic echo findings with high titer positive brucellacapt serology. He was started on medical treatment with doxycycline and rifampin to which gentamicin and ceftriaxone were added and he was planned for surgical intervention. Unfortunately, the patient developed cardiogenic with septic shock before performing surgery and died within 24 h soon after admission.

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Brucella Endocarditis in Prosthetic Valves

Cited by 6 publications

References 10 publications

Endocarditis in the Mediterranean Basin

Endocarditis in the Mediterranean Basin

Brucella prosthetic valve endocarditis: a systematic review

Brucella prosthetic valve endocarditis with septic and cardiogenic shock

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