BSA-capped gold nanoclusters as potential theragnostic for skin diseases: Photoactivation, skin penetration, in vitro, and in vivo toxicity

Abstract

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Gold nanoclusters conjugated berberine reduce inflammation and alleviate neuronal apoptosis by mediating M2 polarization for spinal cord injury repair

“…AuNCs stabilized by BSA were synthesized based on previous reports with slight modifications [ 21 ]. HAuCl 4 solution (5 ml) (10 mM) was combined with 5 ml of BSA solution (50 mg/ml).…”

Engineered Nanostructured Photocatalysts for Cancer Therapy

“…However, bigger Au NCs with peroxo-like orientation of O 2 is likely to facilitate its dissociation to yield O radicals that initiate the oxidation of the Au-S bonds between protein scaffolds and the encapsulated Au NCs to form bigger Au nanoparticles that may lead to fluorescence quenching. There has been great interest in novel design of complex metal-based nanoarchitectures in the last few years [103,104]. Several approaches have been developed to generate advanced hybrid-based structures with synergistic properties.…”

Endocytosed nanogold fiducials for improved in-situ cryo–electron tomography tilt-series alignment

“…In order to get 5-20 nm nanogold fiducials into eukaryotic cells, we incubated the cells with BSA-gold for 1 h before vitrification. Some cytotoxicity has been observed after longer incubation times depending on cell type concentration, incubation time, and gold particle size (Khlebtsov and Dykman, 2011;Leopold et al, 2017;Lillo et al, 2020). We successfully used this method to get BSA-gold fiducials into FIBlamellae of different cell types, including dendritic cells (Fig.…”