BSA optimization and dosimetric assessment for an electron linac based BNCT of deep‐seated brain tumors

Calculation of BNCT Dosimetry for Brain Cancer Based on Kartini Research Reactor Using Phits Code

“…Note that the gamma dose is the sum of the secondary gamma dose which is generated of the 1 H (n, γ) 2 H reaction and the primary gamma dose which is generated from primary gamma-ray sources. In term of BNCT, the weighted dose or commonly known as the total biologically weighted dose, is defined as [35]: Table 3 [36,37,18]. RBE is comparison of absorbed doses of radiation reference sources with test radiation that produce the same biological effect, whereas CBE is a factor of the biological effect used on boron carrier compound [38,39].…”

Design of photon converter and photoneutron target for High power electron accelerator based BNCT

“…After neutron source design, in order to show the performance of the designed target for BNCT application, produced neutron in the neutron target including PC and PNT has been moderated using typical Beam Shaping Assembly (BSA) which consists of 10 cm Iron, 20 cm MgF 2 , 20 cm AlF 3 as the moderators, 1.5 cm LiF as the neutron shield, 5 cm lead for gamma shield and Ni as a collimator (Kasesaz et al, 2013;Rahmani and Shahriari, 2011;Torabi et al, 2014).…”

Investigating a multi-purpose target for electron linac based photoneutron sources for BNCT of deep-seated tumors

“…Because of the advantages such as low costs, small dimensions, high safety, and high social acceptability, these neutron sources can easily find application for in-hospital treatments. These sources are not only suggested for treatment of shallow tumors [15], but also they have proposed to be used for treatment of deeper ones [16,11,17].…”

“…By passing through the first target, a cascade shower of bremsstrahlung photons is produced. Related published works have been investigated different geometries of some high-Z materials, such as W, Ta, Re and Pb to be used as the photon converters [11,17,16]. The generated photons participate in (c, n) reaction within the photoneutron target.…”

“…The generated photons participate in (c, n) reaction within the photoneutron target. To be used as such targets, the efficiency of U, Th, W, Ta, Au, Ag, BeD 2 , and Be have been examined in the literature [11,17]. While these simulated sources result in acceptable neutron flux for treatment of deep tumors, they suffer from complicated designing.…”