Bubble column and airlift bioreactor systems for animal cell culture applications

Abstract

Many biopharmaceutical industries have focused on the screening for novel cell lines and producers for manufacturing of advanced therapeutics. Commercial scale productions at reduced cost and improved productivity are only possible with the bioreactor systems. Animal cell culture bioreactors have all started to draw attention in view that 20th century and advanced significantly over the previous few a long time especially with the need for viral vaccine productions, monoclonal antibody productions and in vitro meat productions.To produce these high value-added products in large scales, bioreactor configurations are advanced to reduce investment and operational costs, control the