Building better brains: the pleiotropic function of neurotrophic factors in postnatal cerebellar development
Pia Boxy,
Anders Nykjær,
Lilian Kisiswa
Abstract:The cerebellum is a multifunctional brain region that controls diverse motor and non-motor behaviors. As a result, impairments in the cerebellar architecture and circuitry lead to a vast array of neuropsychiatric and neurodevelopmental disorders. Neurotrophins and neurotrophic growth factors play essential roles in the development as well as maintenance of the central and peripheral nervous system which is crucial for normal brain function. Their timely expression throughout embryonic and postnatal stages is i… Show more
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