‘Bundle of fun’ or ‘bunch of problems’? Case series of khat-related deaths in the UK

Corkery, John; Schifano, Fabrizio; Oyefeso, Adenekan; Ghodse, A. Hamid; Tonia, Thomy; Naidoo, Vinesha; Button, Jennifer

doi:10.3109/09687637.2010.504200

Cited by 41 publications

(38 citation statements)

References 46 publications

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“…Abdominal pain, flushing, sweating, chills, restlessness and anxiety can be observed as well . Mood disturbances and paranoid ideation have been observed in chronic users . Additional reported mephedrone serious effects include hyperthermia, rhabdomyolysis, renal failure and seizures.…”

Section: Synthetic Cathinonesmentioning

confidence: 99%

Novel psychoactive substances of interest for psychiatry

et al. 2015

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Novel psychoactive substances include synthetic cannabinoids, cathinone derivatives, psychedelic phenethylamines, novel stimulants, synthetic opioids, tryptamine derivatives, phencyclidine-like dissociatives, piperazines, GABA-A/B receptor agonists, a range of prescribed medications, psychoactive plants/herbs, and a large series of performance and image enhancing drugs. Users are typically attracted by these substances due to their intense psychoactive effects and likely lack of detection in routine drug screenings. This paper aims at providing psychiatrists with updated knowledge of the clinical pharmacology and psychopathological consequences of the use of these substances. Indeed, these drugs act on a range of neurotransmitter pathways/receptors whose imbalance has been associated with psychopathological conditions, including dopamine, cannabinoid CB1, GABA-A/B, 5-HT2A, glutamate, and k opioid receptors. An overall approach in terms of clinical management is briefly discussed.

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Section: Synthetic Cathinonesmentioning

confidence: 99%

Novel psychoactive substances of interest for psychiatry

et al. 2015

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“…The buds and leaves contain amphetamine-like psycho active substances, which produce euphoria and stimulation 2 . The khat users from Africa and Arabia, who migrated to different countries have disseminated several health problems to these T countries around the globe 3,4 . A recent report accounted that currently 20 million people worldwide regularly used khat 4 .…”

Section: Introductionmentioning

confidence: 99%

Doppler Assessment of the Effect of Chewing Qat on Hemodynamics of the Common Carotid Arteries

Ibrahim¹,

Malik²,

Gameraddin³

2017

J. of Medical Sciences

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“…Mentally and physically, it leads to problems like depression and anxiety, psychosis, impotence, cardiovascular events, liver failure and stomach ulcers among others [7], [12]. Socially, khat chewing results in diversion of household income among poor families and reduced productivity [7], [13].…”

Section: Introductionmentioning

confidence: 99%

Prevalence and Determinants of Khat (Catha edulis) Chewing among High School Students in Eastern Ethiopia: A Cross-Sectional Study

et al. 2012

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BackgroundUse of psychoactive drugs such as khat leaves (Catha edulis) alter moods and emotional state and lead to adverse effects on the health and social life of users. Ethiopia is a major producer and exporter of khat in east Africa and the majority of the khat comes from the eastern part of the country, however, no studies have been conducted to investigate the habit in this area. This study was conducted to assess the prevalence and predictors of khat chewing among high school students in Harar, eastern Ethiopia.MethodologyThe study was conducted among 1,890 secondary school students in Harar town in April 2010. A structured self-administered questionnaire was used for data collection. Descriptive statistics and logistic regression were performed to examine the prevalence and predictors of khat chewing.ResultThe overall prevalence of khat chewing among the sample was 24.2% (95% CI 22.2%–26.2%). About 28.5% of females and 71.5% of males had chewed khat. Older age (OR 1.31; 95% CI 1.16–1.49), male gender (OR 2.10; 95% CI 1.50–2.93), Muslim religion (OR 1.88; 95% CI 1.17–3.04), having friends who chewed khat (OR 7.93; 95% CI 5.40–11.64), and availability of someone with a similar habit in the family (OR 1.50; 95% CI 1.07–2.11) were found to be independent predictors of chewing.ConclusionA significant proportion of students chew khat. The use of khat is significantly associated with age, gender, Muslim religion, peer influence and habit of family and other relatives among students. Measures such as educational campaigns need to be instituted to create awareness among school adolescents and their parents in order to reduce the prevalence of the habit and its adverse social and health consequences.

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‘Bundle of fun’ or ‘bunch of problems’? Case series of khat-related deaths in the UK

Cited by 41 publications

References 46 publications

Novel psychoactive substances of interest for psychiatry

Novel psychoactive substances of interest for psychiatry

Doppler Assessment of the Effect of Chewing Qat on Hemodynamics of the Common Carotid Arteries

Prevalence and Determinants of Khat (Catha edulis) Chewing among High School Students in Eastern Ethiopia: A Cross-Sectional Study

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