Buprenorphine as an adjuvant to 0.5% ropivacaine for ultrasound-guided supraclavicular brachial plexus block: A randomized, double-blind, prospective study

Jain, Neena; Khare, Arvind; Khandelwal, Shubham; Mathur, Pooja; Singh, Maina; Mathur, Veena

doi:10.4103/ijpn.ijpn_23_17

Cited by 6 publications

(4 citation statements)

References 1 publication

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“…Jain et al . [ 13 ] observed that the duration of sensory and motor blockade was prolonged on adding 0.3 mg of buprenorphine in 30 ml of 0.5% of ropivacaine when compared to the placebo group in the supraclavicular block.…”

Section: Discussionmentioning

confidence: 99%

Comparison of duration of analgesic effect of nalbuphine and morphine as an adjuvant to bupivacaine in the supraclavicular block under ultrasound guidance

et al. 2020

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Background: Although many studies are available in the literature that has analyzed the effects of morphine, nalbuphine, and other opioids, no study had compared the effects of nalbuphine versus morphine as an adjuvant to bupivacaine in the supraclavicular block under the guidance of ultrasound. Methodology: A randomized, double-blinded, prospective study was carried out on 60 patients of the American Society of Anesthesiologists Class I and II who were undergoing upper limb surgeries under the supraclavicular block. Patients were randomly allocated into two groups ( n = 30). Group N received 20 ml of 0.5% bupivacaine with 50 μg.kg −1 of nalbuphine, while Group M received 20 ml of 0.5% bupivacaine with 50 μg.kg −1 of morphine. The characteristics of sensory and motor blocks, hemodynamic changes, duration of analgesia, adverse effects, and analgesic requirements were studied at different time intervals. Results: In Group N, there was a statistically significant reduction in the time of onset of sensory block (9.9 ± 3.0 vs. 12.2 ± 2.6 min, P = 0.002) and motor block (14.4 ± 3.6 vs. 19.4 ± 3.6 min, P = 0.0005). The duration of sensory and motor blockade and duration of analgesia were comparable. There was no statistically significant difference regarding block characteristics and hemodynamic parameters. Conclusion: Nalbuphine when added to bupivacaine as an adjuvant had significantly shortened the time of onset of sensory and motor blockade than morphine. However, the duration of analgesia, sensory and motor blockade of nalbuphine versus morphine were comparable.

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Section: Discussionmentioning

confidence: 99%

Comparison of duration of analgesic effect of nalbuphine and morphine as an adjuvant to bupivacaine in the supraclavicular block under ultrasound guidance

et al. 2020

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“…We founded that no patients in both study groups had complication or side effects related to procedure or local anesthetics( intra-arterial injection, intra-neural injection, nausea, vomiting, hypotension, allergic reactions or neurological/cardiac toxicity).This was may be due to use of ultrasound and careful selection of ropivacaine dose. Neena et al, [5] also stated that ropivacaine had wider safety margin and use ultrasound had made minimal chance of complications and side effects. Dae et al, [6] also demonstrated in their study that use of ultrasound in brachial plexus block had higher success rate and minimal chances of complications.…”

Section: Discussionmentioning

confidence: 99%

Effect of Two Different Concentrations of Ropivacaine in Axillary Brachial Plexus Block in Terms of Block Characteristics – A Comparative Study

Panchal¹,

Panchal²,

Mehta³

2019

AAN

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Background: Peripheral nerve block holds an important place in regional anesthesia. Application of ultrasound guidance in nerve blocks had increased success rate and minimize chances of complications. Ropivacaine, newer local anesthetic with wider safety margin, is widely used now a days in peripheral nerve blocks. Aim of our study is to compare two different concentrations of ropivacaine (0.5% and 0.75%) in axillary brachial plexus block in terms of block characteristics. Subjects and Methods: A prospective randomized study was carried out in total of 60 patients, all of them given ultrasound guided axillary brachial plexus block. All patients were randomized into group A (0.5% ropivacaine, 25 ml) and group B(0.75% ropivacaine, 25 ml). Succes rate, onset/ duration of sensory and motor block, duration of postoperative analgesia and complications if any were noted. Results: Both groups were comparable in terms of demographic characterics. There was no significant difference in onset and duration of sensory and motor block, duration of analgesia and patient satisfaction for both groups. Conclusion: 0.5 % ropivacaine and 0.75% ropivacaine, both are safe and effective in axillary brachial plexus block with no added advantage of 0.75 % ropivacaine over 0.5% ropivacaine.

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“…[ 7 ] Assessment of motor block was done by modified Bromage 3 -point score (0-normal motor function with full flexion and extension of elbow, wrist and fingers, 1-decreased motor strength with ability to move fingers and/or wrist only and 2-complete motor blockade with inability to move fingers. [ 8 ] After a minimum of 30 minutes, patients were shifted to the operating room. In the operation theatre, the block was assessed by pinching the surgical area with a plastic clamp.…”

Section: Methodsmentioning

confidence: 99%

A study to evaluate the change in perfusion index as an indicator of successful ultrasound-guided supraclavicular block

Bhardwaj¹,

Lal²,

Malik³

et al. 2021

Indian Journal of Anaesthesia

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Background and Aims: Perfusion index (PI) is a new simple, objective and non-invasive method for evaluation of the success of central neuraxial and peripheral nerve blocks. So, we conducted a study with an aim to evaluate PI as an indicator for success of ultrasound-guided supraclavicular block (SCB). Methods: 65 patients of either sex, age 18–60 years, American Society of Anesthesiologists physical status I and II posted for upper limb surgery under ultrasound (US)-guided SCB were included. PI was recorded at baseline every 2 minutes till 10 minutes and then every 5 minutes till 30 minutes after block. PI ratio was calculated as the ratio between PI at 10 minutes and baseline PI. Sensory and motor blocks were assessed at 5-minutes intervals up to 30 minutes. Descriptive analysis was applied by mean and standard deviation for quantitative, frequency and proportion for categorical variables. Results: Mean PI increased continuously from baseline and reached the maximum at 10 minutes and then slightly decreased up to 30 minutes, but values at subsequent time intervals were quite high as compared to baseline. In case of successful blocks, median PI started increasing 2 minutes after the block and then increased in a linear fashion till 10 minutes, whereas in case of failed blocks, it only increased minimally. Conclusion: PI is an objective and faster indicator for evaluating success of US-guided SCB. A cut-off value of 3.25 for PI and 3.03 for PI ratio showed a fairly good ability with high sensitivity and specificity for predicting the success of SCB.

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Buprenorphine as an adjuvant to 0.5% ropivacaine for ultrasound-guided supraclavicular brachial plexus block: A randomized, double-blind, prospective study

Cited by 6 publications

References 1 publication

Comparison of duration of analgesic effect of nalbuphine and morphine as an adjuvant to bupivacaine in the supraclavicular block under ultrasound guidance

Comparison of duration of analgesic effect of nalbuphine and morphine as an adjuvant to bupivacaine in the supraclavicular block under ultrasound guidance

Effect of Two Different Concentrations of Ropivacaine in Axillary Brachial Plexus Block in Terms of Block Characteristics – A Comparative Study

A study to evaluate the change in perfusion index as an indicator of successful ultrasound-guided supraclavicular block

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