Burn scar carcinoma

Huang, Chih‐Wei; Feng, Chung Ho; Hsiao, Yen-Chang; Chuang, Shiow Shuh; Yang, Jui Yung

doi:10.3109/09546630903386580

Cited by 28 publications

(26 citation statements)

References 24 publications

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“…Most common cancer is Squamous cell carcinoma(71%),followed by basal cell carcinoma(6%),malignant melanoma(5%) and scarcomas(4%) [1] . Also rare case of malignant fibrous histocytoma, dermatofibrosarcoma protuberans, pleomorphic liposarcoma and verrucous carcinoma have been reported in post burn patient [1,2,3,4] . Adenocarcinoma in burn scar is extremely rare, total 5 cases have been reported and one case out of 5 was of IDC breast.…”

Section: Discussionmentioning

confidence: 99%

"Post Burn Ductal Carcinoma of Breast- A Rare Case Report"

2017

IJCRR

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Objective: A 25 years old female presented to outpatient department of General Surgery of Civil Hospital with breast lump. The objective was to investigate and diagnose the case. Material and Methods:The case was clinically examined in General surgery department. FNAC was done to diagnose swelling. The resected tissue was sent to histopathology for confirmation of the diagnosis. Histological analysis and Immunohistochemical staining was done in Pathology department.Results: On FNAC-Infiltrating Ductal Carcinoma of breast.The patient was operated and tumor was resected. On gross examination, growth identified measures 4x3.5x2.5cm 3 , Cut surface is whitish solid, well defined and firm to hard.On histological examination tumor was diagnosed to be Poorly Differentiated Ductal Carcinoma of Breast. Immuno-histo-chemical staining revealed that the cells were positive for Estrogen receptor and Progesterone receptor. This case was to be Post burn Ductal Carcinoma of breast. Conclusion:Malignancy arising from Burn scar is rare, Squamous cell Carcinoma is most common Burn scar neoplasia and adenocarcinoma is extremely rare. So such cases should be thoroughly examined and followed.

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Section: Discussionmentioning

confidence: 99%

"Post Burn Ductal Carcinoma of Breast- A Rare Case Report"

2017

IJCRR

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“…The average latent period for development of a post-burn malignancy is 30 years. [27] Squamous cell carcinoma is the commonest tumor arising in old BS (71%) followed by basal cell carcinoma (6%), malignant melanoma (5%) and sarcomas (4%). [2] There are rare case reports of malignant fibrous histiocytoma, dermatofibrosarcoma protuberans, pleomorphic liposarcoma and verrucous carcinoma in post-burn patients.…”

Section: Discussionmentioning

confidence: 99%

“…[2] There are rare case reports of malignant fibrous histiocytoma, dermatofibrosarcoma protuberans, pleomorphic liposarcoma and verrucous carcinoma in post-burn patients. [2367] Adenocarcinoma arising in post-BS is extremely rare. An extensive literature search revealed four cases of AC arising in burn scars, out of which one was a metastatic AC in a burnt arm from a lung primary, while three were reported as AC arising in the previously burnt breast/mammary area.…”

Section: Discussionmentioning

confidence: 99%

“…Malignant transformation rarely occurs in grafted skin, and hence rapid epithelization and prompt skin grafting should be promoted. [47]…”

Section: Discussionmentioning

confidence: 99%

“…[1234567] Squamous cell carcinoma is the most common type, others being basal cell carcinoma, malignant melanoma and rarely sarcomas. [123] Adenocarcinoma (AC) is an extremely rare malignancy arising in BS with only four cases reported in the literature till date.…”

Section: Introductionmentioning

confidence: 99%

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Post-burn duct carcinoma breast: An unusual case report

Singh

Rao

Jain

2013

J Cytol

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Malignancies arising from burn scars though rare are well documented in the literature; squamous cell carcinoma is the most common burn scar neoplasm, and adenocarcinoma is an extremely uncommon and rarely reported tumor in these scars. We hereby report a case of a young woman who presented with a rapidly growing lump in a scar in the mammary region that sustained severe burns 20 years back. It was diagnosed as duct carcinoma breast on cytology and later confirmed on histopathology and immunohistochemistry. The case mandates regular follow-up of patients with post-burn scars, and any lump arising in that region should be promptly investigated.

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Fabrication and Characterization of Saffron Stamen Aqueous Extract Controlled Release System as Potential Topical Treatment of Thermal Burn Wounds

et al. 2021

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In our study, we aimed the preparation of Saffron stamen aqueous extract (SSAE) loaded chitosan nanoparticles (CNPs) to be used topically for thermal burns. First, biological activity tests such as DNA binding, DNA cleavage and antibacterial activity were performed to determine the effectiveness of SSAE to be encapsulated. Additionally, a genotoxicity test was performed for the reliability of SSAE. Ionic gelation method was used for encapsulation, and SSAE-loaded CNPs were obtained. Average particle size, zeta potential, polydispersity index (PdI), morphology, and releasing kinetics of the SSAE-loaded CNPs and blank CNPs were determined. DNA binding showed that SSAE interacted with DNA electrostatically. It was determined that all doses of SSAE used in hydrolytic and oxidative DNA cleavage experiments cleave DNA. As a result of the Ames / Salmonella test, it was found that 1,25 mg SSAE was not genotoxic. Then, this concentration was used in nanoparticle synthesis. As a result of DLS analysis, it was determined that SSAE-loaded CNPs have an average size of 57.61 � 1.234 nm, 0.175 � 0.008 PdI, and + 14 � 0.755 mV zeta potential. Encapsulation efficiency and loading capacity of SSAE-loaded CNPs calculated as 71.76 % and 2,64 % respectively. As a result of releasing kinetics, it was determined that 79.54 % of SSAE was released after 168 hours. Antibacterial results revealed that SSAE loaded CNPs were more effective against bacteria than blank SSAE.

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Burn scar carcinoma

Cited by 28 publications

References 24 publications

"Post Burn Ductal Carcinoma of Breast- A Rare Case Report"

"Post Burn Ductal Carcinoma of Breast- A Rare Case Report"

Post-burn duct carcinoma breast: An unusual case report

Fabrication and Characterization of Saffron Stamen Aqueous Extract Controlled Release System as Potential Topical Treatment of Thermal Burn Wounds

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