Burn scar pleomorphic sarcoma—case report

Mello, Daniel Francisco; Carneiro, Stephanie; Gonçalves, Karen Chicol; Jorge, Douglas

doi:10.1007/s00238-011-0598-6

Cited by 1 publication

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“…Current workup and treatment of burn scar UPS should not differ from sporadic UPS. The majority of the few cases of previously reported burn scar UPS have been localized lesions as seen in Table 1, save for the patient reported here and the one case reported by Yamamura et al 6,26–34 As mentioned above, because distinguishing between indolent and aggressive forms of UPS is difficult at the present, it might just be that the two cases developed aggressive forms of UPS during the latent period since burn injury. One may speculate that the longer the duration between burn and diagnosis, the higher possibility of metastasis, but based on the cases seen in Table 1, there does not seem to be a correlation.…”

Section: Discussionmentioning

confidence: 60%

Undifferentiated Pleomorphic Sarcoma of a Chronic Burn Scar of the Knee With Lymph Node Metastasis

Choi

Jin

Kim

et al. 2021

The International Journal of Lower Extremity Wounds

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Malignant transformation of chronic burn scars are usually toward cutaneous lineages, including squamous cell carcinoma, basal cell carcinoma, and malignant melanoma. Sarcomas are less common. Undifferentiated pleomorphic sarcoma(UPS) is a subtype of soft tissue sarcoma with storiform-pleomorphic cells of uncertain origin, and has sparingly been reported to arise from burn scars. The majority are localized lesions probably due to the spatial distance of mesenchymal cells from the epithelium. The authors describe a rare case of UPS of the chronic burn scar of his knee with ipsilateral femoral and external iliac lymph node metastasis.

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