CA1-projecting subiculum neurons facilitate object–place learning

Abstract

Recent anatomical evidence suggests a functionally significant back-projection pathway from the subiculum to CA1. Here we show that the afferent circuitry of CA1-projecting subicular neurons is biased by inputs from CA1 inhibitory neurons as well as visual cortex, but lacks input from entorhinal cortex. Efferents of the CA1-projecting subiculum neurons also target perirhinal cortex, Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:

Subanesthetic ketamine reactivates adult cortical plasticity to restore vision from amblyopia

“…CNMF-E extracts the spatial footprints of neurons and their associated temporal calcium activity after iteratively solving the constrained matrix factorization problem. See more detailed information in our published work (Sun et al, 2019). To assess single cell Ca++ signal responses, we measured peak calcium event amplitudes and summed calcium event amplitudes from extracted neurons ( Figure S7).…”

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Robust Population Single Neuronal Calcium Signal Extraction Using SCOUT Allows for Longitudinal Analysis of Behavior-associated Neural Ensemble Dynamics

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