Cadmium telluride semiconductor detector for improved spatial and energy resolution radioisotopic imaging

Abbaspour, Samira; Moeini, Babak; Islamian, Jalil Pirayesh

doi:10.4103/1450-1147.203079

Cited by 56 publications

(18 citation statements)

References 55 publications

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“…Our industrial collaborator DECTRIS (Baden-Dättwil, Switzerland) provided us with a 2D gamma detector prototype with a native resolution of 487×195 pixels and a pixel size of 172 μ m×172 μ m. The detector technology of DECTRIS is based on Hybrid Photon Counting (HPC) and cadmium telluride (CdTe) sensor material [12]. Its quantum efficiency (QE) at 140.5 keV is 31% [13]. A high QE is crucial as only ≈ 1% or less of the injected tracer activity arrives in the lymphatics.…”

Section: Methodsmentioning

confidence: 99%

Augmenting camera images with gamma detector data

et al. 2019

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Background Squamous cell carcinoma in the head and neck region is one of the most widespread cancers with high morbidity. Classic treatment comprises the complete removal of the lymphatics together with the cancerous tissue. Recent studies have shown that such interventions are only required in 30% of the patients. Sentinel lymph node biopsy is an alternative method to stage the malignancy in a less invasive manner and to avoid overtreatment. In this paper, we present a novel approach that enables a future augmented reality device which improves the biopsy procedure by visual means. Methods We propose a co-calibration scheme for axis-aligned miniature cameras with pinholes of a gamma ray collimating and sensing device and show results gained by experiments, based on a calibration target visible for both modalities. Results Visual inspection and quantitative evaluation of the augmentation of optical camera images with gamma information are congruent with known gamma source landmarks. Conclusions Combining a multi-pinhole collimator with axis-aligned miniature cameras to augment optical images using gamma detector data is promising. As such, our approach might be applicable for breast cancer and melanoma staging as well, which are also based on sentinel lymph node biopsy.

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Section: Methodsmentioning

confidence: 99%

Augmenting camera images with gamma detector data

et al. 2019

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“…The energy of the photon is directly proportional to the total induced charge on each electrode. Semiconductor detectors have higher energy resolution due to this direct conversion when compared to scintillation detectors [46,47]. The mobility-lifetime products for electrons and holes, µτ e and µτ h , of the semiconductor are very important, as they dictate the mean drift length which is the average distance a charge carrier can travel before being captured by traps or recombination centers.…”

Section: Semiconductor Detectorsmentioning

confidence: 99%

State-of-the-art challenges and emerging technologies in radiation detection for nuclear medicine imaging: A review

Enlow

Abbaszadeh

2023

Front. Phys.

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Single photon emission computed tomography (SPECT) and positron emission tomography (PET) are established medical imaging modalities that have been implemented for decades, but improvements in detector design and camera electronics are needed for advancement of both imaging technologies. Detectors are arguably the most important aspect of the systems. Similar to SPECT, PET typically relies on indirect conversion of gamma radiation via scintillators coupled with photosensors used to convert optical photons produced by the scintillator into an electrical signal. PET detectors are defined by their energy resolution, timing resolution, and spatial resolution, all of which affect and determine the image quality. Improvements in energy resolution have been shown by increasing the brightness of the scintillator utilizing materials like cerium bromide (CeBr3) or switching to a direct conversion detector, such as cadmium zinc telluride (CZT) or thallium bromide (TlBr). Timing resolution for PET is a focal point of the current research. Improving the timing resolution improves the signal-to-noise of the PET system and is integral to the implementation of time-of-flight PET. By utilizing novel configurations, such as side readouts on scintillators, timing resolution has been improved dramatically. Similarly, metascintillators, which use complex combinations for the scintillator material, have also shown improvements to the timing resolution. Additional research has focused on using Cherenkov light emission in scintillators to further improve the timing resolution. Other research is focused on using convolutional neural networks and other signal processing to enhance timing resolution. Lastly, aside from acollinearity and positron range, spatial resolution is impacted by the PET detector, therefore improving the intrinsic spatial resolution of the detector will allow for smaller features to be imaged. One method for improving the spatial resolution is to use unique configurations with layered scintillators. Additionally, monolithic scintillators have also been shown to have reduced spatial resolution. The future for both SPECT and PET image system advancement will depend on continued development of the detectors via many different pathways including materials, signal processing, physics, and novel configurations. In this review article, we will discuss challenges and emerging technologies for state-of-the-art radiation detectors utilized in PET and SPECT.

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“…In the literature, there are several studies on the use of the CdTe detector [9][10][11][12] and registration by it of high-intensity gamma-radiation in the range of energies of 0.06-1.2 MeV. In papers [12][13][14][15], CdTe detectors are studied together with operational characteristics, temperature stability, and reliability of the detector's measurements.…”

Section: Literature Review and Problem Statementmentioning

confidence: 99%

“…Analysis of the data published in [4][5][6][7][8][9][10][11][12][13][14][15], makes it possible to establish the following. In the studied sources, little attention was paid to the problems of assessment of the accuracy of the proposed methods.…”

Section: Literature Review and Problem Statementmentioning

confidence: 99%