Cafeteria diet induces progressive changes in hypothalamic mechanisms involved in food intake control at different feeding periods in female rats

Lazzarino, Gisela Paola; Acutain, María Florencia; Canesini, Guillermina; Andreoli, María Florencia; Ramos, Jorge G.

doi:10.1016/j.mce.2019.110542

Cited by 12 publications

(13 citation statements)

References 73 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Yet, the highly processed label also recognizes that homemade versions of these products (e.g., homemade cookies) that are created through the use of processed ingredients (e.g., sugar, white flour) are also prone to be consumed in addictive ways. However, research that links a diet high in ultraprocessed foods with negative health consequences has increased rapidly over the last decade (31,70,125,131). Thus, in the current review, we have chosen to adopt the term ultraprocessed foods for consistency with this growing literature.…”

Section: A Note On Terminologymentioning

confidence: 99%

Is Food Addictive? A Review of the Science

2021

View full text Add to dashboard Cite

As ultraprocessed foods (i.e., foods composed of mostly cheap industrial sources of dietary energy and nutrients plus additives) have become more abundant in our food supply, rates of obesity and diet-related disease have increased simultaneously. Food addiction has emerged as a phenotype of significant empirical interest within the past decade, conceptualized most commonly as a substance-based addiction to ultraprocessed foods. We detail ( a) how approaches used to understand substance-use disorders may be applicable for operationalizing food addiction, ( b) evidence for the reinforcing potential of ingredients in ultraprocessed foods that may drive compulsive consumptions, ( c) the utility of conceptualizing food addiction as a substance-use disorder versus a behavioral addiction, and ( d) clinical and policy implications that may follow if ultraprocessed foods exhibit an addictive potential. Broadly, the existing literature suggests biological and behavioral parallels between food addiction and substance addictions, with ultraprocessed foods high in both added fat and refined carbohydrates being most implicated in addictive-like eating. Future research priorities are also discussed, including the need for longitudinal studies and the potential negative impact of addictive ultraprocessed foods on children. Expected final online publication date for the Annual Review of Nutrition, Volume 41 is September 2021. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

show abstract

Section: A Note On Terminologymentioning

confidence: 99%

Is Food Addictive? A Review of the Science

2021

View full text Add to dashboard Cite

show abstract

“…The overconsumption of energy-dense foods, rich in sugar, has contributed to the rapid increase of metabolic disorders [ 1 ]. Non-nutritive sweeteners (NNS) are food additives with the advantage of providing high potency in sweetness but with few or no caloric content [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Effects of Non-Nutritive Sweeteners on Energy Intake, Body Weight and Postprandial Glycemia in Healthy and with Altered Glycemic Response Rats

Ramos-García

Blé-Castillo

García-Vázquez

et al. 2021

Foods

View full text Add to dashboard Cite

The aim of this study was to evaluate the effects of non-nutritive sweeteners (NNS) consumption on energy intake, body weight and postprandial glycemia in healthy and with altered glycemic response rats. Animals on normal diet (ND) or high-fat diet (HFD) were divided to receive NNS (sucralose, aspartame, stevia, rebaudioside A) or nutritive sweeteners (glucose, sucrose) for 8 weeks. The NNS were administered at doses equivalent to the human acceptable daily intake (ADI). A test using rapidly digestible starch was performed before and after treatments to estimate glycemic response. No effects of NNS consumption were observed on energy intake or body weight. Sucrose provoked an increased fluid consumption, however, energy intake, and weight gain were not altered. In ND, no effects of NNS on glycemic response were observed. In HFD, the glycemic response was increased after sucralose and stevia when only the final tolerance test was considered, however, after including the baseline test, these results were no longer significant compared to glucose. These findings provide further evidence suggesting that at the recommended doses, NNS do not alter feeding behavior, body weight or glycemic tolerance in healthy and with altered glycemic rats.

show abstract

“…Gonadal tissue was isolated from the GAM complex by using the microdissection technique previously described (Lazzarino et al, 2019), modi ed and adapted for caiman embryo samples. Brie y, GAM samples stored at -80°C were embedded in an OCT cryo-embedding matrix (CRYOPLAST® Biopack, Argentina) and 300-µm-thick GAM serial transverse sections were obtained using a cryostat (Leica CM 1860, Leica Biosystems, IL, USA) at an operating temperature of -20ºC.…”

Section: Image Analysis and Quanti Cation Of Molecules Revealed By Ihcmentioning

confidence: 99%

Disruption of the developmental programming of the gonad of the broad snouted caiman (Caiman latirostris) after in ovo exposure to atrazine

Canesini

Galoppo

Tavalieri

et al. 2023

Environ Sci Pollut Res

Self Cite

View full text Add to dashboard Cite

Environmental exposure to agrochemicals during early stages of development can induce subtle alterations that could permanently affect normal physiology. Previously, we reported that in ovo exposure to atrazine (ATZ) disrupts testicular histoarchitecture in postnatal caimans (Caiman latirostris). To assess whether such alterations are the result of disruption of gonadal developmental programming, this study aimed to evaluate the expression of histofunctional biomarkers (VASA, ER, PR, PCNA, and aromatase) and genes involved in gonadal development and differentiation (amh, sox-9, sf-1 and cyp19-a1) in the gonads of male and female caiman embryos and to assess the effect of ATZ exposure on these biomarkers and genes in the gonads of male embryos. Our results suggest that amh, aromatase and sox-9 play a role in sex determination and gonadal differentiation. In male caiman embryos, ATZ exposure increased aromatase expression and altered the temporal expression pattern of amh and sox-9 evidencing an ATZ-induced disruption of gonadal developmental programming. Since the effects of ATZ are consistent across all vertebrate classes, the ATZ-mediated disruptive effects here observed could be present in other vertebrate species.

show abstract

Cafeteria diet induces progressive changes in hypothalamic mechanisms involved in food intake control at different feeding periods in female rats

Cited by 12 publications

References 73 publications

Is Food Addictive? A Review of the Science

Is Food Addictive? A Review of the Science

Effects of Non-Nutritive Sweeteners on Energy Intake, Body Weight and Postprandial Glycemia in Healthy and with Altered Glycemic Response Rats

Disruption of the developmental programming of the gonad of the broad snouted caiman (Caiman latirostris) after in ovo exposure to atrazine

Contact Info

Product

Resources

About