Calixarene‐Based Phosphorus Ligands

Novel synthetic route for (parent) phosphetanes, phospholanes, phosphinanes and phosphepanes

“…4 To customise and tune (transition)metal complexes used in catalysis, a variety of phosphines have been and are still being synthesised. 5–7…”

“…Generally speaking, special reaction conditions such as liquid ammonia as solvent, 12 dilution conditions, slow fractional distillation over long columns for work-up or tedious multi-step syntheses are necessary. 5,11,13 This is accompanied by a lack of selectivity and low yields. In addition, sterically demanding substituents such as tert -butyl groups in the carbon backbone or phenyl groups attached to the phosphorus atom in the starting materials are necessary to stabilise the phosphorus-containing heterocycles by these approaches, which makes access to the corresponding parent (P–H) compounds even more difficult.…”

Fast and Selective β-C–H Borylation of N-Heterocycles with a Supramolecular Iridium Catalyst: Circumventing Deactivation Pathways and Mechanistic Insights

“…As such, the last century has witnessed tremendous efforts devoted to the development of catalytic technologies for such purposes . In this context, homogeneous transition metal-catalyzed processes occupy a central place since the ease of ligand fine-tuning is advantageous to disclose new reactivity patterns . Most of these transformations require the use of preactivated coupling partners to selectively form new carbon–carbon or carbon–heteroatom bonds at specific positions at the expenses of generating substantial amounts of side-products including those from the preactivation reactions too .…”

Manganese(I)-Catalyzed Asymmetric Hydrophosphination of α,β-Unsaturated Carbonyl Derivatives

“…Phosphines containing carbon stereocenters make up an important class of compounds that have found applications in asymmetric catalysis, both as ligands, in combination with various transition metals, and in their own right as chiral organocatalysts. , These phosphines are often difficult to access, due to their laborious, multistep synthesis, and therefore are expensive. In addition, their preparation commonly requires stoichiometric amounts of chiral auxiliaries or performing optical resolutions of preformed racemates . These aspects have hindered ready access to the library of chiral derivatives of phosphine ligands …”

“…In addition, their preparation commonly requires stoichiometric amounts of chiral auxiliaries or performing optical resolutions of preformed racemates. 4 These aspects have hindered ready access to the library of chiral derivatives of phosphine ligands. 5 …”