Cambios epidemiológicos de la endocarditis infecciosa sobre válvula nativa

Castillo, Juan Carlos; Anguita, Manuel; Ruiz, Manuel Concha; Peña, Luisa; Santisteban, Marta; Puentes, Miguel; Arizón, José M.; Lezo, José Suárez de

doi:10.1016/j.recesp.2011.03.011

Cited by 37 publications

(19 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Our results indicated that age ≥ 60 years (OR = 6.861, 0.94–50.1), congestive heart failure (OR = 8.854, 1.34–54.7), diabetes (OR = 7.224, 1.17–44.7), and Staphylococcus aureus or negative tuberculosis infection (OR = 18.81, 2.39–148.2) were major risk factors for the prognosis of IE patients. Our results exhibited some differences from other studies [4, 12, 13], in which Staphylococcus aureus infections, heart failure and PVE were considered major risk factors that could result in emergency surgery or death. Streptococcus and Staphylococcus were the main pathogens, whereas Staphylococcus epidermidis , coagulase-negative staphylococci and HACKE genus (including Haemophilus species, Aggregatibacter species, Cardiobacterium hominis, Eikenella corrodens and Kingella species) were detected less often compared to other countries [14].…”

Section: Discussioncontrasting

confidence: 99%

The changing epidemiology and clinical features of infective endocarditis: A retrospective study of 196 episodes in a teaching hospital in China

Zhu

Zhang

2017

BMC Cardiovasc Disord

View full text Add to dashboard Cite

BackgroundInfective endocarditis is an uncommon but life-threatening infectious disease. To our knowledge, current investigations of the characteristics of infective endocarditis in our region are scarce. In this study, we aimed to investigate the changes in the epidemiology and clinical features of infective endocarditis.MethodsA retrospective analysis of clinical data was performed using 196 infective endocarditis cases diagnosed between June 2004 and December 2012 at The First Affiliated Hospital of China Medical University. A comparative analysis of clinical risk factors was also included.ResultsThe mean age of the patient cohort was 43.5 (29.0–55.8) years old. Of the 196 cases studied, 128 cases (65.3%) were left native valve infective endocarditis, 13 cases (6.6%) were left prosthetic valve infective endocarditis, and 47 cases (24%) were right valve infective endocarditis. In addition to natural valve endocarditis, many patients also exhibited various types of cardiopathy: 72 cases (36.7%) had congenital cardiovascular malformations, 37 cases (18.9%) had idiopathic mitral valve prolapse and 31 cases (15.8%) had no significant cardiac disease. The primary clinical manifestations that were observed included 168 cases with fever (85.7%), 131 cases with anemia (66.8%), 114 cases with hematuria (58.2%) and 58 cases with splenomegaly (29.6%). Positive blood cultures were detected in 96 cases (49%); the most commonly detected organism was Streptococcus viridans (41 cases; 42.7%), followed by 18 cases (18.8%) of Staphylococcus aureus and 10 cases (10.4%) of Enterococcus. With respect to risk factors, infection with Staphylococcus aureus or gram-negative bacilli (OR = 18.81, 95%CI = 2.39–148.2), congestive heart failure (OR = 8.854, 95%CI = 1.34–54.7), diabetes (OR = 7.224, 95%CI = 1.17–44.7) and age ≥ 60 years (OR = 6.861, 95%CI = 0.94–50.1) were major prognostic risk factors.ConclusionInfective endocarditis is more common than previously believed, but there are regional differences with respect to the epidemiological and clinical characteristics of infective endocarditis, and its etiology is diverse and complicated. Our study of the clinically diagnosed cases of infective endocarditis verified the regional characteristics of infective endocarditis using a straightforward retrospective analysis. The geographic variations we observed in the study will be of important value to clinical diagnosis in our region.

show abstract

Section: Discussioncontrasting

confidence: 99%

The changing epidemiology and clinical features of infective endocarditis: A retrospective study of 196 episodes in a teaching hospital in China

Zhu

Zhang

2017

BMC Cardiovasc Disord

View full text Add to dashboard Cite

show abstract

“…In Spain, several studies have shown similar results. Castillo et al 3 reported 228 patients studied between 1987 and 2009: the incidence of predisposing rheumatic valvular heart disease and congenital heart diseases fell significantly, mitral valve prolapse was the most common heart disease, and the proportion of patients with no predisposing heart disease increased significantly (from 25% to 57% in recent years). The incidence of late prosthetic endocarditis has increased more than that of early prosthetic endocarditis.…”

Section: Cardiac Risk Factorsmentioning

confidence: 99%

“…2 The population at risk of infection are no longer young people with known rheumatic valvular heart disease and are now elderly people with no apparent valve disease. 3 In addition, the mechanism of infection has also altered; a history of dental intervention before the onset symptoms has become anecdotal, while a substantial percentage of patients are infected by in-hospital procedures. 4 Infective endocarditis is an uncommon disease, with an estimated incidence of 3.1 to 3.7 episodes per 100 000 inhabitants/year.…”

Section: Introductionmentioning

confidence: 99%

Epidemiology of Infective Endocarditis in Spain in the Last 20 Years

Fernández-Hidalgo

2013

Revista Española de Cardiología (English Edition)

View full text Add to dashboard Cite

“…Destaca el aumento del diagnóstico de EI en los últimos dos años del estudio, lo que podría indicar un aumento de la prevalencia de endocarditis en nuestra región o un subdiagnóstico de endocarditis en los años previos. La edad de nuestros pacientes estudiados es en promedio 49,7 años, similar a estudios nacionales 3,15,16 e internacionales 8,12 , También es similar la mayor afección de pacientes de sexo masculino con una razón aproximada a una razón 2:1 respecto de las mujeres. 3,8,15,16 En nuestro estudio existió una mayor proporción de pacientes con endocarditis en válvulas protésicas que en otros estudios nacionales 3,15 , pero es similar a la proporcionada por estudios internacionales 17 en los cuales se encuentra en un 20% de los pacientes.…”

Section: Discussionunclassified

“…La dificultad para disminuir la mortalidad puede ser explicada por la constante evolución epidemiológica de esta enfermedad 1, 2, 7 . Clásicamente, la endocarditis se producía en pacientes susceptibles con valvulopatía causada por enfermedad reumática 2,7,8,9 y el Streptococcus viridans era el patógeno más frecuente 7,8,9 . Actualmente, ha disminuido la proporción de pacientes con antecedentes de enfermedad reumática o con hallazgos ecocardiográficos sugerentes 10 y el microorganismo más frecuentemente encontrado es el Staphylococcus aureus, comprometiendo a más del 25% de los pacientes con EI 1 , 8, 10, 11 lo que podría estar en relación con el aumento de individuos con válvulas protésicas, inmunodeprimidos, en hemodiálisis y usuarios de drogas endovenosas 12 .…”

Section: Introductionunclassified

Endocarditis infecciosa en Hospital de Talca, período 1998 - 2015

Cruz

Migueles

2018

Rev Chil Cardiol

View full text Add to dashboard Cite

Introducción: La endocarditis infecciosa es una enfermedad con una alta mortalidad que se ha mantenido estable en los últimos años pese a avances en su diagnóstico y tratamiento.Objetivo: Evaluar las características clínicas de los pacientes con Endocarditis Infecciosa tratados en el Hospital de Talca. Materiales y métodos:Estudio retrospectivo en que se revisaron las historias clínicas de los pacientes con endocarditis infecciosa atendidos entre 1998 y 2015 en el Hospital Regional de Talca.Resultados: Se encontraron 62 pacientes con endocarditis infecciosa con un promedio de edad de 49,7 años, 61,2% de ellos de sexo masculino, 21% de ellos con válvula protésica y 13% con antecedentes de enfermedad reumática. Las comorbilidades más frecuentes fueron hipertensión arterial, diabetes mellitus y enfermedad renal crónica. El 72,5% de los pacientes se presentaron con síndrome febril y soplo asociado. Un 87,1% presentaban vegetaciones al ecocardiograma. El 67,1% de los pacientes tenía hemocultivo positivo, de los cuales el microorganismo más frecuente fue el Staphylococcus aureus (22,6%). Un 24,2 % de los pacientes requirieron tratamiento quirúrgico. La mortalidad intrahospitalaria fue de un 19,3%. Conclusiones: Material and Methods:Retrospective study in which the clinical records of patients with infective endocarditis treated between 1998 and 2015 at Hospital Regional de Talca were reviewed.Results: 62 patients with infective endocarditis were identified. The median age was 49,7 years, 61,2% were males. 21% carried one or more prosthetic heart valve and 13% had previous rheumatic valve disease. The most common comorbidities were hypertension, diabetes, and chronic kidney disease. 72,5% presented with fever and a cardiac murmur, 87,1% had vegetations in echocardiography. In 67% of patients blood cultures were positive and22,6% of them had blood cultures positive for Staphylococcus aureus. 24,2 % of patients required hearth surgery. Hospital mortality was 19,3%. Conclusions:The clinical characteristics of patients included in this series were similar to those found in national and international studies, Hospital mortality was high

show abstract

Cambios epidemiológicos de la endocarditis infecciosa sobre válvula nativa

Cited by 37 publications

References 20 publications

The changing epidemiology and clinical features of infective endocarditis: A retrospective study of 196 episodes in a teaching hospital in China

The changing epidemiology and clinical features of infective endocarditis: A retrospective study of 196 episodes in a teaching hospital in China

Epidemiology of Infective Endocarditis in Spain in the Last 20 Years

Endocarditis infecciosa en Hospital de Talca, período 1998 - 2015

Contact Info

Product

Resources

About