Can bone mineral density loss in the non-weight bearing distal forearm predict mortality?

Hauger, Annette Vogt; Bergland, Astrid; Holvik, Kristin; Emaus, Nina; Strand, Bjørn Heine

doi:10.1016/j.bone.2020.115347

Cited by 3 publications

(2 citation statements)

References 43 publications

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“…4 . It is evident in several clinical studies (Zhang et al 2020 ; Hauger et al 2020 ; Gupta et al 2020 ; Petrovic et al 2019 ; Nilsson et al 2019 ; Wishart et al 1995 ) that bone loss appears to accelerate with increasing age. In this context, compared to the radiograph used in this study (Fig.…”

Section: Resultsmentioning

confidence: 99%

Finite element analysis of bone remodelling with piezoelectric effects using an open-source framework

Bansod

Kebbach

Kluess

et al. 2021

Biomech Model Mechanobiol

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Bone tissue exhibits piezoelectric properties and thus is capable of transforming mechanical stress into electrical potential. Piezoelectricity has been shown to play a vital role in bone adaptation and remodelling processes. Therefore, to better understand the interplay between mechanical and electrical stimulation during these processes, strain-adaptive bone remodelling models without and with considering the piezoelectric effect were simulated using the Python-based open-source software framework. To discretise numerical attributes, the finite element method (FEM) was used for the spatial variables and an explicit Euler scheme for the temporal derivatives. The predicted bone apparent density distributions were qualitatively and quantitatively evaluated against the radiographic scan of a human proximal femur and the bone apparent density calculated using a bone mineral density (BMD) calibration phantom, respectively. Additionally, the effect of the initial bone density on the resulting predicted density distribution was investigated globally and locally. The simulation results showed that the electrically stimulated bone surface enhanced bone deposition and these are in good agreement with previous findings from the literature. Moreover, mechanical stimuli due to daily physical activities could be supported by therapeutic electrical stimulation to reduce bone loss in case of physical impairment or osteoporosis. The bone remodelling algorithm implemented using an open-source software framework facilitates easy accessibility and reproducibility of finite element analysis made.

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Section: Resultsmentioning

confidence: 99%

Finite element analysis of bone remodelling with piezoelectric effects using an open-source framework

Bansod

Kebbach

Kluess

et al. 2021

Biomech Model Mechanobiol

View full text Add to dashboard Cite

show abstract

“…Another study found that low BMD in the distal forearm, categorized as osteopenia and osteoporosis, was associated with increased mortality, and the association was only slightly attenuated by taking osteoporotic fractures into account [6]. This may suggest that low BMD is more powerful predictor of death than an increased risk of fracture [7].…”

Section: Introductionmentioning

confidence: 99%

The Risk of Osteoporotic Forearm Fractures in Postmenopausal Women in a Siberian Population Sample

Mazurenko

Rymar

Щербакова

et al. 2020

JPM

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The reduction in bone and muscle mass increases in menopausal women and poses a threat to the loss of self-dependence in the elderly. The aim of the study was to assess the frequency of osteoporotic forearm fractures (OFF) in postmenopausal women and to study their association with risk factors for chronic non-communicable diseases (NCD). The study was based on the Russian arm of the Health, Alcohol and Psychosocial Factors In Eastern Europe (HAPIEE) project (Novosibirsk). In a subsample of postmenopausal women aged 55–84 years old (n = 2005), we assessed the history of OFF during the last 3 years and risk factors for fracture and common NCD/. Cross-sectional associations between OFF history and potential determinants were analyzed using multivariable-adjusted logistic regression. A history of OFF in the last 3 years was found in 3.9% women. In a multivariable-adjusted model, the risk of OFF was directly associated with smoking in the past (OR = 2.23; 95% Cl 1.10–4.55), total cholesterol level higher than 200 mg/dL (OR = 1.98; 95% Cl 1.19–3.29), and it was inversely associated with body mass index (OR = 0.91; 95% Cl 0.86–0.96). In studied population sample of postmenopausal women the cross-sectional determinants of osteoporotic forearm fractures were smoking in the past and high total cholesterol value; body mass index protectively related to the risk of osteoporotic fractures. These findings might have implications for fracture prevention in postmenopausal women.

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Is Radiographic Osteoporotic Hip Morphology A Predictor For High Mortality Following Intertrochanteric Femur Fractures?

Okkaoğlu

Özdemir

Yaradilmis

et al. 2022

Injury

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Can bone mineral density loss in the non-weight bearing distal forearm predict mortality?

Cited by 3 publications

References 43 publications

Finite element analysis of bone remodelling with piezoelectric effects using an open-source framework

Finite element analysis of bone remodelling with piezoelectric effects using an open-source framework

The Risk of Osteoporotic Forearm Fractures in Postmenopausal Women in a Siberian Population Sample

Is Radiographic Osteoporotic Hip Morphology A Predictor For High Mortality Following Intertrochanteric Femur Fractures?

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