Can Colonic Manometry Studies Be Done on the Day of Colonic Motility Catheter Placement?

Ammoury, Rana; Emhardt, John D.; Aitchison, William B.; Horn, Debra; Croffie, Joseph M.

doi:10.1097/mpg.0b013e31824ac64c

Cited by 16 publications

(19 citation statements)

References 23 publications

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“…Patients, research staff and hospital administrators alike do not appreciate prolonged, overnight studies. While the data utilized in this study were from recordings commencing the day after colonoscopic placement of the catheter, we have since shown that colonic motility is detectable within hours of catheter placement, a fact also confirmed by others 30 …”

Section: Discussionsupporting

confidence: 81%

Classification of normal and abnormal colonic motility based on cross‐correlations of pancolonic manometry data

Wiklendt¹,

Mohammed²,

Scott³

et al. 2013

Neurogastroenterology Motil

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Section: Discussionsupporting

confidence: 81%

Classification of normal and abnormal colonic motility based on cross‐correlations of pancolonic manometry data

Wiklendt¹,

Mohammed²,

Scott³

et al. 2013

Neurogastroenterology Motil

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“…24 We used sevoflurane anesthesia protocol as we have shown previously that anesthesia protocol does not alter colonic motility study findings. 25 In our study octreotide was overall well tolerated. Six patients had mild discomfort with administration of subcutaneous octreotide.…”

Section: Discussionmentioning

confidence: 79%

Effect of Octreotide on Colonic Motility in Pediatric Patients With Chronic Recalcitrant Constipation

Parashette

Waseem

Horn

et al. 2015

J. pediatr. gastroenterol. nutr.

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Objective: To study the effect of octreotide on colonic motility in pediatric patients with recalcitrant chronic constipation/encopresis and other suspected colonic motility disorders.Methods: This was a non-randomized, single center, open label, prospective study evaluating the effect of a single subcutaneous dose of octreotide on colonic motility Results: Thirteen patients (5 male) were enrolled in the study. The age range was 4.6-16.2 years. Eleven patients (84%) had normal colonic manometry and two patients (16%) had colonic neuropathy. Motility Index (MI) (mm Hg) for the 15 minutes before and after octreotide infusion was 6.03 ± 1.26 (95% CI, 5.35-6.72), and 5.32 ± 1.66 (95% CI, 4.42-6.23) respectively with p-value of 0.08. MI for the 30 minutes before and after octreotide infusion was 6.89 ± 1.37 (95% CI, 6.14-7.64) and 6.71 ± 1.47 (95% CI, 5.91-7.52) respectively with p-value of 0.55. MI for the 45 minutes before and after octreotide infusion was 7.73 ± 1.32 (95% CI, 7.01-8.45) and 7.53 ± 1.38 (95% CI, respectively with p-value of 0.8. Conclusion: Our study showed that administration of octreotide resulted in no significant changes in colonic motility index in pediatric patients with chronic recalcitrant constipation.

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“…On the other hand, Ammoury et al. found no difference in the MI or study interpretation when comparing results after catheter placement or the next day . However, their study population does not seem to represent patients with significant defecation disorders as the majority of the subjects (17/20) had a normal CM already on day 1 that remained normal on day 2.…”

Section: Discussionmentioning

confidence: 91%

“…Some centers perform the study on the same day right after catheter placement under anesthesia and others perform it the following day. A previous study showed that there is no difference . Another study suggested that there may be more colonic motor events recorded the day after anesthesia .…”

Section: Introductionmentioning

confidence: 92%

Prospective evaluation of same day versus next day colon manometry results in children with medical refractory constipation

Arbizu

Nurko

Heinz

et al. 2017

Neurogastroenterology Motil

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Background We evaluated the change on colon manometry (CM) parameters and interpretation comparing results when the study is performed the same day after the motility catheter is placed under anesthesia or the following day. Methods CM catheter was placed with colonoscopy under anesthesia and recorded on day 1 and repeated on day 2. Study parameters including motility index (MI) during fasting, post-prandial and post-Bisacodyl challenge phase; gastrocolonic response; number, presence and propagation of high amplitude propagating contractions (HAPCs); and, study interpretation were compared between both days. Key Results MI (fasting, post-Bisacodyl phase, p<0.05), HAPC number (10.1 vs. 6.6, p=0.01) and proportion of patients having HAPCs (92% vs. 70%, p=0.002) was significantly higher on day 2 vs. day 1. HAPC propagation improved on day 2 vs. day 1 (fully propagated, 49% vs. 37%; partially propagated, 43% vs. 33%; absent 8% vs. 30%). Study interpretation changed from day 1 to day 2. On day 1, 37% had a normal study and 63% had an abnormal study. On day 2, all patients with a normal study on day 1 remained normal, and patients with an abnormal study on day 1, 53% remained abnormal and 47% had a normal study. Conclusions & Inferences CM parameters are affected the day catheter is placed with colonoscopy under anesthesia. The number, presence and propagation of HAPCs was significantly higher/improved on day 2 compared to day 1. Overall, CM interpretation changed from abnormal to normal from day 1 to day 2 in 47% of the patients.

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Can Colonic Manometry Studies Be Done on the Day of Colonic Motility Catheter Placement?

Abstract: Colonic manometry studies can be conducted as early as 4 hours following catheter placement with either propofol or sevoflurane used for anesthesia.

Cited by 16 publications

References 23 publications

Classification of normal and abnormal colonic motility based on cross‐correlations of pancolonic manometry data

Classification of normal and abnormal colonic motility based on cross‐correlations of pancolonic manometry data

Effect of Octreotide on Colonic Motility in Pediatric Patients With Chronic Recalcitrant Constipation

Prospective evaluation of same day versus next day colon manometry results in children with medical refractory constipation

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