Can green synthesized propolis loaded silver nanoparticulate gel enhance wound healing caused by burns?

Patil, Sharvil; Nilesh, Desai; Mahadik, Kakasaheb R.; Paradkar, Anant

doi:10.1016/j.eujim.2015.03.002

Cited by 17 publications

(11 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Stapf, 80 Nyctanthes arbor-tristis L., 81 Naringi crenulata (Roxb.) Nicolson, 82 Phytophthora infestans, 83 Biophytum sensitivum, 84 Propolis, 85 and Bryonia laciniosa L. 86 Most of these extracts possess inherent antibacterial and antimicrobial activity, which makes them appropriate for wound care. The importance of the presence of antimicrobial agents in wound dressing is their substantial role in controlling the microorganism colonization and subsequent proliferation, which helps accelerating wound healing process.…”

Section: Green-synthesized Metal Nanoparticles Using Plantsmentioning

confidence: 99%

Natural product-based nanomedicines for wound healing purposes: therapeutic targets and drug delivery systems

Hajialyani¹,

Tewari²,

Sobarzo‐Sánchez³

et al. 2018

IJN

177

113

View full text Add to dashboard Cite

Wound healing process is an intricate sequence of well-orchestrated biochemical and cellular phenomena to restore the integrity of the skin and subcutaneous tissue. Several plant extracts and their phytoconstituents are known as a promising alternative for wound healing agents due to the presence of diverse active components, ease of access, and their limited side effects. The development of nanotechnological methods can help to improve the efficacy of different therapeutics as well as herbal-based products. Here, we present a review of the efficacy of the plant based-nanomaterials in the management of wounds and discuss the involved therapeutic targets. For this purpose, a profound search has been conducted on in vitro, in vivo, and/or clinical evidences evaluating the efficacy and pharmacological mechanisms of natural product-based nanostructures on different types of wounds. Different pharmacological targets are involved in the wound healing effects of herbal-based nanostructures, including suppressing the production of inflammatory cytokines and inflammatory transduction cascades, reducing oxidative factors and enhancing antioxidative enzymes, and promoting neovascularization and angiogenic pathways through increasing the expression of vascular endothelial growth factor, fibroblast growth factor, and platelet-derived growth factor. Moreover, nanostructure of plant extracts and their phytochemicals can enhance their bioavailability, control their release in the form of sustained delivery systems to the wound site, and enhance the permeability of these therapeutics to the underlying skin layers, which are all necessary for the healing process. Overall, various plant extracts and their natural compounds, used in nanoformulations, have demonstrated high activity in the management of wounds and thus can be assumed as future pharmaceutical drugs.

show abstract

Section: Green-synthesized Metal Nanoparticles Using Plantsmentioning

confidence: 99%

Natural product-based nanomedicines for wound healing purposes: therapeutic targets and drug delivery systems

Hajialyani¹,

Tewari²,

Sobarzo‐Sánchez³

et al. 2018

IJN

177

113

View full text Add to dashboard Cite

show abstract

“…The nanosilver synthesized with addition of propolis in situ can reduce minimal inhibitory concentration of nanosilver and accelerate the healing of burn wounds in rats. 86 Healing of burn wounds needs to exclude ultraviolet exposure in order to mitigate the adverse reactions such as scar hyperplasia. Arora et al 87 showed that nanosilver with a size of 10-40 nm can protect the DNA of glial cells from UVB radiation damage, indicating that nanosilver may protect the burn wound from the impact of ultraviolet radiation.…”

Section: Extending the Function Of Nanosilvermentioning

confidence: 99%

Nanotechnology-enabled materials for hemostatic and anti-infection treatments in orthopedic surgery

Sun¹,

Lv²,

Bai³

et al. 2018

IJN

View full text Add to dashboard Cite

The hemostatic and anti-infection treatments in the field of orthopedics are always the pivotal yet challenging topics. In the first part of this review, synthesized or naturally derived nanoscale agents and materials for hemostatic treatment in orthopedic surgery are introduced. The hemostatic mechanisms and the safety concerns of these nanotechnology-enabled materials are discussed. Beside the materials to meet hemostatic needs in orthopedic surgery, the need for antimicrobial or anti-infection strategy in orthopedic surgery also becomes urgent. Nanosilver and its derivatives have the most consistent anti-infective effect and thus high translational potential for clinical applications. In the second part, the factors affecting the antimicrobial effect of nanosilver and its application status are summarized. Finally, the status and translational potential of various nanotechnology-enabled materials and agents for hemostatic and anti-infective treatments in orthopedic surgery are discussed.

show abstract

“…On the other hand, as nanotechnology can offer new opportunities for propolis application, in another line of research, nanosized particles have been developed. Patil et al [130] have obtained and characterized silver nanoparticles containing propolis [130]. Propolis nanoparticles have also been obtained employing lipid carriers.…”

Section: Nanoparticles and Innovation Productsmentioning

confidence: 99%

Functional Properties of Brazilian Propolis: From Chemical Composition Until the Market

Berretta¹,

Arruda²,

Miguel³

et al. 2017

Superfood and Functional Food - An Overview of Their Processing and Utilization

View full text Add to dashboard Cite

Propolis is a product obtained from resins and exudates of different plants from different regions in order to protect the comb, with peculiar organoleptic, chemicals and biological properties. Considering this, this chapter presents the types of Brazilian propolis as the types available nowadays, their chemical compositions, as well as, some of their important biological properties enabling employing them as important health food, such as antimicrobial, antioxidant, and immunomodulation action. Various "in vivo" and clinical trial studies, conducted in different regions, on the safety and dosage of propolis, technologies used to obtain propolis extract, and several innovative presentations of this promising bee product are also presented in this chapter. Finally, this chapter aims to present the regulatory affairs, potential market for propolis around the world, and perspectives for a near future.

show abstract

Can green synthesized propolis loaded silver nanoparticulate gel enhance wound healing caused by burns?

Cited by 17 publications

References 36 publications

Natural product-based nanomedicines for wound healing purposes: therapeutic targets and drug delivery systems

Natural product-based nanomedicines for wound healing purposes: therapeutic targets and drug delivery systems

Nanotechnology-enabled materials for hemostatic and anti-infection treatments in orthopedic surgery

Functional Properties of Brazilian Propolis: From Chemical Composition Until the Market

Contact Info

Product

Resources

About