Can HPLC be used as an ideal methodology instead of Hb Electrophoresis for the diagnosis of hemoglobinopathies in a routine clinical laboratory of under-resource country like Nepal? Is the change necessary?
The study proposes a ResNet34 DL model for automated SCD diagnosis using mIEF for Hb S, achieving 90.1% accuracy in classifying Hb variants. The model's precision suggests it could reduce costs and the reliance on the need for expert diagnosis.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.