Can MR contribute to the diagnosis of nephroblastomatosis?

Hausegger, K. A.; Fötter, R.; Flückiger, F; Sorantin, Erich

doi:10.1007/bf02011736

Cited by 14 publications

(1 citation statement)

References 8 publications

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“…Wie in der Literatur beschrieben [12,22] waren die Nephroblastoseherde auf Kontrastmittel-verstärkten T 1 -gewichteten Aufnahmen erkennbar, da sie im Gegensatz zu dem normalen Nierengewebe weniger oder gar kein Kontrastmittel aufnehmen. Mit der Sonographie läßt sich die Nephroblastomatose von normalem Nierengewebe kaum differenzieren [25].…”

Section: Nephroblastomatoseunclassified

Kernspintomographische Diagnostik benigner und prämaligner abdomineller Tumoren im Kindesalter

et al. 1999

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Section: Nephroblastomatoseunclassified

Kernspintomographische Diagnostik benigner und prämaligner abdomineller Tumoren im Kindesalter

et al. 1999

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Malignant Renal Tumors

Shehata

Naguib

Lin

et al. 2014

Pediatric Malignancies: Pathology and Imaging

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Renal tumors account for approximately 6-7 % of all pediatric cancers, with Wilms' tumor being the most common malignancy [ 1 , 2 ]. Current classifi cation and staging criteria for renal tumors, aided by advances in molecular and cytogenetic abnormalities, have allowed accurate diagnostic, staging, and therapeutic protocols [ 2 ], elucidated new categories of renal neoplasms, and created more inclusive classifi cation (Table 10.1 ) [ 2 , 3 ]. Overview of Imaging FeaturesThe imaging evaluation of a suspected pediatric renal mass should always begin with ultrasound. Sonography is readily available, can be performed without sedation and intravenous contrast, and does not expose the child to ionizing radiation. If a renal mass is identifi ed on ultrasound, further evaluation of the renal vessels and inferior vena cava (IVC) with both gray scale and color Doppler images are required to detect vascular extension, present in up to 10 % of cases [ 4 ]. Further evaluation with contrast enhanced computed tomography (CT) or magnetic resonance imaging (MRI) is also required for local staging of the mass prior to any intervention, as per the guidelines of the Children's Oncology Group (COG). Either modality can be used, depending on institutional availability and expertise [ 5 ].In keeping with the As Low As Reasonably Achievable (ALARA) principle regarding ionizing radiation exposure, pre-contrast and multiphase contrast enhanced CT images are not required for diagnosis or staging of pediatric renal tumors [ 6 ]. A single-phase study in the portal venous phase (approximately 50 s after contrast injection) suffi ciently stages a renal tumor and delineates relevant anatomy. Multiplanar CT reconstructions or multiplanar scanning with MRI can confi rm the renal origin of the mass and assess its relationship to vital structures such as the renal vessels. If a partial nephrectomy is being considered, multiphase images are helpful to determine the relationship of the mass to the renal vessels and collecting system. A CT of the chest is required in all malignant renal tumors to evaluate for potential lung metastasis. Wilm's Tumor Defi nitionWilms' tumor ( syn: nephroblastoma), a malignant neoplasm originating from nephrogenic blastemal cells, is the second most common malignant, solid extracranial tumor in children [ 1 , 7 , 8 ]. It is a traditional blastematous tumor, exhibiting various stages of embryonic development and multiple lines of differentiation. Clinical Features and EpidemiologyIn children ranging from 0 to 15 years of age, Wilms' tumor occurs in seven to ten cases per million annually (1 in 10,000 children) and accounts for approximately 95 % of renal tumors, and comprises 6-7 % of all pediatric tumors [ 7 , 9 , 10 ]. It is the fi fth most common pediatric tumor and the second most common intraabdominal tumor in children [ 11 ].

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Abdominelle Venen

Vogl¹

1995

MR-Angiographie Und MR-Tomographie Des Gefäßsystems

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Can MR contribute to the diagnosis of nephroblastomatosis?

Cited by 14 publications

References 8 publications

Kernspintomographische Diagnostik benigner und prämaligner abdomineller Tumoren im Kindesalter

Kernspintomographische Diagnostik benigner und prämaligner abdomineller Tumoren im Kindesalter

Malignant Renal Tumors

Abdominelle Venen

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