Can platelet indices predict obstruction level of pulmonary vascular bed in patients with acute pulmonary embolism?

Günay, Ersin; Ulaşlı, Sevinç Sarınç; Kaçar, Emre; Halici, Bilal; Ünlü, Ebru; Tünay, Kamil; Özkeçeci, Gülay; Köken, Tülay; Ünlü, Mehmet

doi:10.1111/crj.12031

Cited by 49 publications

(40 citation statements)

References 25 publications

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“…In this aspect, MPV may have association with APE 13 . In one study, MPV was found to be an independent predictor of early death in APE 14 and another study speculated that it can be used for the determination of disease severity 15 .…”

mentioning

confidence: 99%

The New Diagnostic Marker For Acute Pulmonary Embolism In Emergency Department; Mean Platelet Volume

Talay¹,

Ocak²,

Alçelik³

et al. 2014

Afr H. Sci.

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mentioning

confidence: 99%

The New Diagnostic Marker For Acute Pulmonary Embolism In Emergency Department; Mean Platelet Volume

Talay¹,

Ocak²,

Alçelik³

et al. 2014

Afr H. Sci.

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“…Moreover, MPV was higher in massive PE patients compared to the patients with sub-massive or non-massive PE. Günay et al (17) found that MPV levels were correlated with the pulmonary arterial occlusion level assessed by Computed tomography pulmonary arterial obstruction index ratio (CTPAOIR). These findings suggest that pulmonary arterial occlusion level that was the indicator of the massive PE can be predicted with the increased levels of MPV.…”

Section: Discussionmentioning

confidence: 99%

Mean Platelet Volume: A Simple Tool For Early Risk Stratification Of Pulmonary Embolism

Şentürk¹,

Kanbay²,

Erdoğan³

et al. 2017

Eastern J Med

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“…Researchers consistently reported that PDW may be related to increased platelet activation in patients with PE (1,20). Wang et al reported that PDW was significantly higher in the chronic obstructive pulmonary disease (COPD) patients with PE compared to the COPD patients without PE and also reported that higher PDW significantly correlate with bilateral thrombus in pulmonary artery branches (2).…”

Section: Discussionmentioning

confidence: 99%

“…Wang et al reported that PDW was significantly higher in the chronic obstructive pulmonary disease (COPD) patients with PE compared to the COPD patients without PE and also reported that higher PDW significantly correlate with bilateral thrombus in pulmonary artery branches (2). Günay et al reported that MPV, PDW levels, and platelet levels were higher in massive and submassive patient groups with PE compared to control subjects (20).…”

Section: Discussionmentioning

confidence: 99%

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Does platelet indices play a role in the distinction of pulmonary embolism clinical forms?

Telo¹,

Kırkıl²,

Kaman³

et al. 2017

J Turgut Ozal Med Cent

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Aim: The aim of this study is to investigate the changes in platelet indexes, including mean platelet volume (MPV), platelet distribution width (PDW) and platelet count (PC), in patients with acute pulmonary embolism (PE), in addition to evaluating the diagnostic value in clinical forms. Material and methods: The study consisted of 84 patients with PE and the control group consisted of 40 healthy subjects. PE patients were divided into two groups in accordance with the clinical forms as 60 submassive and 24 nonmassive. The differences in platelet count, MPV, PDW, PC, D-dimer, and other indicators were analyzed between the two groups. Venous peripheral blood samples to measure the MPV, PDW and PC were acquired on admission. Results: MPV levels were found to be statistically higher in the submassive group compared to the nonmassive group and the control group (p<0.01 and p<0.001, respectively). PDW levels were found to be statistically higher in the submassive group compared to the non-massive group and control group (p=0.027 and p<0.001, respectively). PC was significantly lower in the submassive group compared to the non-massive group and control group (p=0.022 and p<0.001, respectively). It was determined that a positive correlation existed between the MPV and right ventricular diameter (RVD) (r=0.27, p<0.01). Conclusion: High MPV and PDW levels and low PC may be indicators of the severity of acute PE. Also, the correlation between the MPV and RVD suggests that MPV can be used as a marker of right ventricular function.

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Can platelet indices predict obstruction level of pulmonary vascular bed in patients with acute pulmonary embolism?

Abstract: Platelet indices, MPV and PDW, can be used for the determination of disease severity, and lead to therapeutic strategies for PE patients.

Cited by 49 publications

References 25 publications

The New Diagnostic Marker For Acute Pulmonary Embolism In Emergency Department; Mean Platelet Volume

The New Diagnostic Marker For Acute Pulmonary Embolism In Emergency Department; Mean Platelet Volume

Mean Platelet Volume: A Simple Tool For Early Risk Stratification Of Pulmonary Embolism

Does platelet indices play a role in the distinction of pulmonary embolism clinical forms?

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