Can Vagus Nerve Stimulation Help Migraine?

Lenaerts, Marc; Oommen, Kalarickal J.; Couch, J. R.; Skaggs, Valerie J.

doi:10.1111/j.1468-2982.2008.01538.x

Cited by 86 publications

(57 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Half the patients had nearly complete disappearance of headaches (mean follow-up 13 months) (40), which is an interesting result that needs to be confirmed in an RCT.…”

Section: Occipital Nerve Stimulation (Ons)mentioning

confidence: 86%

Targeting pericranial nerve branches to treat migraine: Current approaches and perspectives

et al. 2015

View full text Add to dashboard Cite

Background: Migraine is a highly prevalent neurological disorders and a major individual and societal burden. Migraine is not curable at the present time, but it is amenable to acute symptomatic and preventive pharmacotherapies. Summary: Since the latter are frequently unsatisfactory, other treatment strategies have been used or are being explored. In particular, interventions targeting pericranial nerves are now part of the migraine armamentarium. We will critically review some of them, such as invasive and noninvasive neurostimulation, therapeutic blocks and surgical decompressions. Conclusions: Although current knowledge on migraine pathophysiology suggests a central nervous system dysfunction, there is some evidence that interventions targeting peripheral nerves are able to modulate neuronal circuits involved in pain control and that they could be useful in some selected patients. Larger, well-designed and comparative trials are needed to appraise the respective advantages, disadvantages and indications of most interventions discussed here.

show abstract

“…Half the patients had nearly complete disappearance of headaches (mean follow-up 13 months) (40), which is an interesting result that needs to be confirmed in an RCT.…”

Section: Occipital Nerve Stimulation (Ons)mentioning

confidence: 86%

Targeting pericranial nerve branches to treat migraine: Current approaches and perspectives

et al. 2015

View full text Add to dashboard Cite

show abstract

“…At 5 years of follow-up after beginning the stimulation, Kuba et al reported 64.4% of patients were responders whose 15.5% experienced 90% seizure reduction, and 5.5% were seizure-free (19). Tatum Several studies reported the efficacy of VNS in different disorders except epilepsy such as Lennox-Gastaut syndrome, migraine, depression, Alzheimer disease, multiple sclerosis for postural cerebellar tremor and dysphagia, eating disorders like bulimia nervosa and Tourette syndrome (11,16,17,21,22,23,33). It seems VNS will be a treatment modality for many diseases in the future.…”

Section: Degiorgio Et Al Investigated 195 Patients With Generalizedmentioning

confidence: 99%

Vagal nerve stimulation effects on generalized-partial seizures and medication in adult drug resistans epilepsy patients

Özdoğan

Nurhat²,

Düzkalır³

et al. 2013

Turkish Neurosurgery

View full text Add to dashboard Cite

“…Stimulation of the afferent vagal fibers could potentially modulate the activity of the pathway of trigeminal nerve-mediated pain [32]. An open-label trial of external vagus nerve stimulation to abort migraine attacks in 27 subjects gave pain freedom in 21 % at 2 h [33].…”

Section: Vagus Nerve Stimulationmentioning

confidence: 99%

Treatment of Headache Following Triptan Failure After Successful Triptan Therapy

Lenaerts

Couch

2015

Curr Treat Options Neurol

View full text Add to dashboard Cite

Triptans should remain the first choice in migraine abortive treatment. They are not always effective or adequate for specific patients. Before declaring a triptan in appropriate for a given patient, the provider ought to be analytical about the rationale and especially the use of objective efficacy outcome measures and ensure that treatment is prescribed and used appropriately. Other ergot derivatives, especially dihydroergotamine, may on one hand share common contraindications of triptans but on the other hand can be quite effective where triptans failed. Non-steroids are simple, readily available, and overall safe, and evidence for their efficacy in migraine is plentiful. Opioid analgesics are blatantly overprescribed especially in non-complicated migraine patients. These should be used with great care and restraint and closely monitored. Frequent opioid usage often leads to tolerance, dependence, and medication overuse headache. Neurostimulation is gaining momentum in the armamentarium of migraine management but at the present time remains primarily focused on prophylaxis, yet abortive use is expected to grow.

show abstract

Can Vagus Nerve Stimulation Help Migraine?

Cited by 86 publications

References 15 publications

Targeting pericranial nerve branches to treat migraine: Current approaches and perspectives

Targeting pericranial nerve branches to treat migraine: Current approaches and perspectives

Vagal nerve stimulation effects on generalized-partial seizures and medication in adult drug resistans epilepsy patients

Treatment of Headache Following Triptan Failure After Successful Triptan Therapy

Contact Info

Product

Resources

About