Can we close the barn door before the horses get out? A case study of high genetic loading and subsequent development of psychosis

Roos, J.L.; Lombard, Melinda; Ladikos, A.

doi:10.4314/ajpsy.v14i3.9

Cited by 11 publications

(2 citation statements)

References 9 publications

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“…In die Suid-Afrikaanse konteks is daar die Geestesgesondheidsorgwet van 2002, wat duidelik bepaal dat daar nie onregverdig gediskrimineer mag word teen pasiënte op grond van 'n psigiatriese steurnis nie, en dat verbruikers dieselfde gesondheidsorgdienste moet ontvang as enige ander gesondheidsorgverbruiker (Suid-Afrika 2002). Verdere ontwikkeling van GINA-verwante wetgewing in die Suid-Afrikaanse konteks sal in die toekoms nodig wees (Roos, Lombard & Ladikos 2011).…”

Section: Etiese En Sosiale Aspekte Van Genetiese Raadgewing By Skisofrenieunclassified

Vroeë afwykende niepsigotiese gedrag in skisofrenie

Roos¹

2019

Genetiese Bevindings in ‘N Groep Afrikaners Met Skisofrenie

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Section: Etiese En Sosiale Aspekte Van Genetiese Raadgewing By Skisofrenieunclassified

Vroeë afwykende niepsigotiese gedrag in skisofrenie

Roos¹

2019

Genetiese Bevindings in ‘N Groep Afrikaners Met Skisofrenie

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“…In 'n wetenskaplike brief (Roos et al 2011) is gerapporteer oor 'n 10-jarige Afrikanermeisie (A) wat verwys is vir insluiting in die genetikastudie. Op 16-jarige ouderdom is sy gediagnoseer met 'n psigiatriese steurnis.…”

Section: Hoë Genetiese Lading In 'N Familie En Moontlike Voorspellers Van Psigose In 'N 10-jarige Dogterunclassified

Spesifieke chromosoomgebiede en/of kandidaatgene geïdentifiseer by skisofrenie

Roos¹

2019

Genetiese Bevindings in ‘N Groep Afrikaners Met Skisofrenie

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Tai Chi Quan Versus Physical Therapy on Pain and Cognitive Performance for Elderly People With Chronic Low Back Pain: Study Protocol for a Randomized Controlled Trial

Wang

Zhu

Wang

et al. 2022

Front. Aging Neurosci.

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ObjectivesChronic low back pain has become a major cause of global disability and caused a huge economic burden to society. Physical therapy is a vital strategy for rehabilitation of chronic low back pain. Although several trials have shown that Tai Chi Quan is a beneficial treatment, the comparative effectiveness of Tai Chi Quan versus physical therapy is unknown. We are conducting a randomized controlled trial to assess the effectiveness of Tai Chi Quan versus that of physical therapy in treating chronic low back pain.MethodsWe will perform a single-blind randomized controlled trial on elderly people with chronic low back pain. 138 participants will be randomly assigned to the Tai Chi Quan group (60-min classes, three times per week for 12 weeks) or physical therapy group (10 min of evaluation and warm-up, 40 min of therapist-directed exercise therapy, and 10 min of relaxation, three times per week for 12 weeks) with an allocation of 1:1. The participants will be followed up for 40 weeks for the study of long-term effects. The primary outcomes include pain intensity and back-related function at 12 weeks. Secondary outcomes include lumbar quantitative sensory testing, balance, cognitive function, psychosocial function, cost-effectiveness, compliance and adverse events. We will perform the intention-to-treat analysis for withdrawal and missing data.DiscussionThe study will be the first randomized trial with comparative-effectiveness of Tai Chi Quan and physical therapy for chronic low back pain. Standardized protocol, large sample size, and comprehensive outcomes are important features in this trial. This study aims to determine the feasibility and effectiveness of Tai Chi Quan for low back pain. The results of this study will be beneficial for elderly people with low back pain and medical rehabilitation personnel.Clinical Trial Registrationwww.chictr.org.cn, identifier ChiCTR2000029723.

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Can we close the barn door before the horses get out? A case study of high genetic loading and subsequent development of psychosis

Cited by 11 publications

References 9 publications

Vroeë afwykende niepsigotiese gedrag in skisofrenie

Vroeë afwykende niepsigotiese gedrag in skisofrenie

Spesifieke chromosoomgebiede en/of kandidaatgene geïdentifiseer by skisofrenie

Tai Chi Quan Versus Physical Therapy on Pain and Cognitive Performance for Elderly People With Chronic Low Back Pain: Study Protocol for a Randomized Controlled Trial

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