2024
DOI: 10.9734/ajrb/2024/v14i4300
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Cancer Initiation and Progression: A Comprehensive Review of Carcinogenic Substances, Anti-Cancer Therapies, and Regulatory Frameworks

Aadil Shafi Bhat,
Mizna Ahmed,
Kashif Abbas
et al.

Abstract: Cancer is a multifaceted disease influenced by genetic mutations and environmental factors, including exposure to carcinogens. This review presents an in-depth analysis of the mechanisms driving cancer initiation, focusing on the roles of carcinogenic chemicals, anticancer therapies, and chemo-preventive agents. The discussion encompasses a broad spectrum of carcinogens: chemical agents like polycyclic aromatic hydrocarbons, physical agents such as ionizing radiation, biological agents like viruses, and certai… Show more

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