Cancer pain, anxiety, and depression in admitted patients at a tertiary care hospital: A prospective observational study

Arora, Anshika; Saini, Sunil; Nautiyal, Vipul; Verma, Sunil K.; Gupta, Meenu; Kalra, Bharti; Ahmad, Mushtaq

doi:10.4103/ijpc.ijpc_4_19

Cited by 21 publications

(15 citation statements)

References 19 publications

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“…twitter, WhatsApp.) According to the previous prevalence rate of GERD or heartburn (since dyspepsia prevalence in Saudi Arabia is unknown) of 28.7% ( Alsuwat et al, 2018 ), the sample size (N) was calculated using the following formula: N = z 2 × p × q / d 2 ( Arora et al, 2019 , Alharbi and Ghoraba, 2019 , Alrashed et al, 2019 ); Where: N is the minimum sample size, z is the level of confidence according the normal standard distribution which corresponds to the 95% confidence interval (z = 1.96), p is the prevalence of GERD (0.287), q = (1-p), and d is the desired degree of accuracy or tolerated margin of error which is 5% (0.05). N = (1.96) 2 × 0.29 × (1–0.29) / (0.05) 2 = 314; N = 314 people …”

Section: Methodsmentioning

confidence: 99%

Prevalence and severity of dyspepsia in Saudi Arabia: A survey-based study

Alwhaibi

Alghadeer

Bablghaith

et al. 2020

Saudi Pharmaceutical Journal

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Background and aim Dyspepsia is one of the gastrointestinal diseases that is very common worldwide. Despite its prevalence globally, which ranges between 1.8% and 57%, no study has assessed the prevalence in Saudi Arabia. This study was aimed to investigate the prevalence and severity of dyspepsia in the general population of Saudi Arabia. Methods A modified Short-Form Leeds Dyspepsia Questionnaire (SF-LDQ) was utilized to conduct our study. The questionnaire score ranges between 0 and 32, where zero indicated no dyspepsia, a score of 1–8 indicated mild dyspepsia, a score of 9–15 indicated moderate dyspepsia and a score of higher than 15 represented severe dyspepsia. Socio-demographic data of the participants including age, gender, marital status, BMI, job description, insurance, and education level were collected. Using Statistical Package for Social Sciences version 21.0 (SPSS), a univariate analysis was performed to assess the association of participants characteristics with the prevalence of dyspepsia, whereas logistic regression analysis was used to correlate their characteristics with the severity of dyspepsia. Results During a period of one month, March 1st to 31st 2019, a total of 778 participants have completed the survey. Most of them were females accounting for 68% of the population, married (63.9%), middle aged (range 34–51 years old) and literate with high school education (72.3%). Ninety two percent (92%) of the study population were found to experience dyspepsia. However, there is no significant association between socio-demographic characteristics and dyspepsia or its severity as well. Conclusion The prevalence of dyspepsia in Saudi Arabia is the highest in the gulf region which would potentially lead to more GI complications, and associate to poor health and economic outcomes. Education programs are essential to raise the people awareness of dyspepsia and the appropriate ways to prevent it.

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Section: Methodsmentioning

confidence: 99%

Prevalence and severity of dyspepsia in Saudi Arabia: A survey-based study

Alwhaibi

Alghadeer

Bablghaith

et al. 2020

Saudi Pharmaceutical Journal

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“…[ 8 ] Both anxiety and depression may decrease patients’ capability to tolerate the illness burden and aggressive treatment regimens, which extends periods of hospitalization, worsens quality of life and elevates mortality rates. [ 9 ]…”

Section: Introductionmentioning

confidence: 99%

Prevalence and correlation of anxiety and depression on the prognosis of postoperative non-small-cell lung cancer patients in North China

Huang

Zhang²,

Li³

et al. 2020

Medicine

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Identify the prevalence of postoperative anxiety and depression as well as their correlations with clinical features and survival profiles in non-small-cell lung cancer (NSCLC) patients who underwent resection. Four hundred NSCLC patients who underwent resection were recruited, and their anxiety and depression were assessed by hospital anxiety and depression scale (HADS) at discharge after surgery. Besides, 480 healthy controls (HCs) were also enrolled and assessed by HADS. The HADS-Anxiety score of NSCLC patients (7.8 ± 3.9) was greatly higher than that of HCs (4.8 ± 2.7), and the anxiety prevalence of NSCLC patients (49.6%) were dramatically increased compared with HCs (13.8%). Furthermore, the HADS-Depression score (7.2 ± 3.6) of NSCLC patients was considerably increased compared with HCs (4.2 ± 2.6), and the depression prevalence of NSCLC patients (38.3%) was significantly raised compared with HCs (10.0%). Besides, anxiety correlated with gender, marital status, hypertension, diabetes, pathological differentiation, tumor size, lymph node metastasis, TNM stage and carcinoembryonic antigen level, meanwhile, depression correlated with marital status, employment status before surgery, diabetes, pathological differentiation, and TNM stage in NSCLC patients. Additionally, the anxiety and depression predicted shorter disease-free survival in NSCLC patients. And the anxiety predicted worse overall survival (OS), while no association of depression with OS was observed in NSCLC patients. Post-operative anxiety and depression are highly prevalent and implicated in the ongoing care and prognosis prediction in NSCLC patients who underwent resection.

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“…In clinical practice, these depression symptoms should not just be neglected as they could affect the quality of life, adherence to the treatment plan, psychological perception from other physical symptoms, and most importantly, the prognosis of the disease. Nevertheless, depression in cancer patients was often neglected and had not been well managed [16]. This study also showed that 75% of the patients had difficulty in performing daily activities due to persistent symptoms.…”

Section: Resultsmentioning

confidence: 76%

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2023

J. Med. Chem. Sci.

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Pain symptoms could affect the quality of life of cancer patients. Quality of sleep and depression were two considerable parameters associated with quality of life. Cancer patients with pain as symptoms would have a higher probability of experiencing depression, which might affect sleep quality. This was an observational research with a cross-sectional study conducted in Haji Adam Malik General Public Hospital from April-September 2021. The severity of depression and quality of sleep was measured with Patient Health Questionnaire (PHQ-9) and Pittsburgh Sleep Quality Index (PSQI), respectively. There was a significant relationship between pain and depression based on the Visual Analogue Scale (VAS) and Numerical Rating Scale (NRS) with p < 0.05. A significant relationship was also seen between pain and the ability to perform activities (symptom-related difficulty) based on the VAS and NRS scale with p < 0.05. However, no significant relationship was found between pain and quality of sleep of the patients in VAS and NRS scales. Furthermore, there was no significant difference in pain scale between VAS and NRS. Pain symptom was one of the factors associated with depression and the ability to perform activities in cancer patients. A more comprehensive interview is required to assess the possible causes of poor sleep quality experienced in most cancer patients.

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Cancer pain, anxiety, and depression in admitted patients at a tertiary care hospital: A prospective observational study

Cited by 21 publications

References 19 publications

Prevalence and severity of dyspepsia in Saudi Arabia: A survey-based study

Prevalence and severity of dyspepsia in Saudi Arabia: A survey-based study

Prevalence and correlation of anxiety and depression on the prognosis of postoperative non-small-cell lung cancer patients in North China

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