Canine Parvovirus

Singh, Mithilesh; Chander, Vikas; Nandi, Sukdeb

doi:10.1007/978-981-13-9073-9_12

Cited by 1 publication

(1 citation statement)

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“…CPV-2 is a nonenveloped virus with a single-stranded negative-sense DNA genome [3]. The genetic diversity of CPV-2 resulted in the emergence of 5 distinct antigenic variants such as CPV-2a, CPV-2b, new CPV-2a, new CPV-2b, and CPV-2c with amino acid differences mainly restricted to the capsid VP2 protein [4]. CPV-2 are ubiquitous and sturdy viruses that remain viable for more than one year in the favorable environment [5,6] and are transmitted usually by the faeco-oral route [7,8].…”

Section: Introductionmentioning

confidence: 99%

Canine Parvovirus-2: An Emerging Threat to Young Pets

Singh¹,

Manikandan²,

De³

et al. 2023

Veterinary Medicine and Science

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Canine parvovirus-2 (CPV-2) is a highly contagious and key enteropathogen affecting the canine population around the globe by causing canine parvoviral enteritis (CPVE) and vomition. CPVE is one of the the leading causes of morbidity and mortality in puppies and young dogs. Over the years, five distinct antigenic variants of CPV-2, namely CPV-2a, CPV-2b, new CPV-2a, new CPV-2b, and CPV-2c, have emerged throughout the world. CPV-2 infects a diverse range of wild animals, and the newer variants of CPV-2 have expanded their host range to include felines. Despite the availability of highly specific diagnostics and efficacious vaccines, CPV-2 outbreaks have been reported globally due to the emergence of newer antigenic variants, expansion of the viral host range, and vaccination failures. The present chapter describes the latest information pertaining to virus properties and replication, disease manifestations in animals, and an additional recent updates on diagnostic, prevention and control strategies of CPV-2.

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