Canine Zinc-Responsive Dermatosis

Colombini, S.

doi:10.1016/s0195-5616(99)50133-2

Cited by 27 publications

(38 citation statements)

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“…Fifty‐nine per cent of such dogs develop cutaneous lesions when they are older than 2 years 22 . Although skin lesions usually occur during puberty, oestrus, stress, pregnancy or concurrent disease may precipitate the dermatosis 23 . Cutaneous lesions in Syndrome 1 include focal erythema, alopecia, scaling, and crusting that primarily develop on the head.…”

Section: Discussionmentioning

confidence: 99%

Zinc‐responsive dermatosis in goats suggestive of hereditary malabsorption: two field cases

Krametter-Froetscher

Hauser

Baumgartner

2005

Veterinary Dermatology

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Two cases of zinc deficiency in dairy goats from different flocks and not associated with a zinc-deficient diet are described. Hard, dry, hyperkeratotic skin, hair loss and pruritus especially prominent on the back, legs, udder, face and ears were the most common clinical signs. Skin biopsy findings revealed a mixture of orthokeratotic and parakeratotic hyperkeratosis. On initial examination, serum zinc concentrations were low in both goats (461 microg L(-1) and 521 microg L(-1), respectively). Although mild skin lesions persisted during the early stages of zinc supplementation, skin lesions completely resolved after prolonged oral zinc supplementation. Withdrawal of zinc supplementation resulted in re-appearance of lesions in both animals. Case 2 gave birth to two kids, one of which showed mild skin lesions at 8 months of age together with a low serum zinc concentration (434 microg L(-1)), suggestive of hereditary zinc malabsorption. The other kid remained free of skin lesions and had a serum zinc concentration (530 microg L(-1)) within the normal range. On the basis of historical and clinical findings, the cases presented here more closely resemble Syndrome 1 hereditary zinc deficiency as seen in Nordic dog breeds rather than other zinc deficiency conditions seen in other species. It is suggested that zinc deficiency in these goats was due to hereditary malabsorption of dietary zinc. This is the first descriptive study of this condition in goats. Life-long zinc supplementation may be necessary in such patients.

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Section: Discussionmentioning

confidence: 99%

Zinc‐responsive dermatosis in goats suggestive of hereditary malabsorption: two field cases

Krametter-Froetscher

Hauser

Baumgartner

2005

Veterinary Dermatology

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“…The keratinization defect in alpacas 22) is primarily orthokeratotic. The measurement of serum or blood concentrations of zinc cannot reliably separate affected animals from normals 3,4,14,24) . The dermatosis responds completely and rapidly to zinc (eg.…”

Section: Discussionmentioning

confidence: 99%

Ichthyosis in a Nigerian Dwarf Goat

2014

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Abstract:A 4-year-old Nigerian Dwarf goat presented with a long history of nonpruritic, scaly skin noticed since it was acquired at 3 weeks of age. Dermatologic examination revealed widespread large, white, nonadherent scales covering the entire skin. Histopathologic findings were characterized by noninflammatory compact diffuse orthokeratotic hyperkeratosis. Oral vitamin A therapy resulted in an approximate 85% reduction of the scaling with no reports of adverse effects. This is the first reported case of ichthyosis in the goat. Oral vitamin A may be beneficial for the management of caprine ichthyosis.

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“…In turn, blood trace metal concentrations are influenced by dietary intake as well as interactions with other elements and compounds (Kempson and Lombi 2011). Adequate Zn is essential for the production of normal hair, and a deficiency results in abnormal keratinization and weakened hair fibers in many species (Colombini 1999;Goldberg and Lenzy 2010;Reis 1992). The significantly lower Zn in case juveniles may indicate deficiency and, therefore, lower hair strength.…”

Section: Discussionmentioning

confidence: 99%