Capillary and Microchip Electrophoresis

Kitagawa, Fumihiko

doi:10.2116/analsci.highlights2008

Cited by 6 publications

(5 citation statements)

References 17 publications

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“…Furthermore, HA and His could be separated with the SEFs of 83~87 in MCE-LVSEP. By employing the developed approach, sensitive analyses of various cationic compounds including biogenic amines, amino acids, metal complexes, inorganic cations, and so on, are expected in MCE [35].…”

Section: Discussionmentioning

confidence: 99%

LVSEP Analysis of Cationic Analytes in Cationic Polymer-Coating Microchannel Prepared by Vacuum-Drying Method

2021

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To improve the detection sensitivity of cationic analytes with simple experimental procedures in microchip electrophoresis (MCE), large-volume sample stacking with an electroosmotic flow (EOF) pump (LVSEP) was performed in polymer-coated microchannels. At first, cationic polybrene (PB) was employed as the coating polymer to reverse the EOF. In the LVSEP analyses, however, the PB-coated microchannel gave insufficient enrichments and broader peaks for cationic standard dyes. By the application of neutral poly(vinyl alcohol) and cationic poly(allylamine) mixture-coating, on the other hand, good enrichments of histamine were achieved by LVSEP with a sensitive enhancement factor of 120.

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Section: Discussionmentioning

confidence: 99%

LVSEP Analysis of Cationic Analytes in Cationic Polymer-Coating Microchannel Prepared by Vacuum-Drying Method

2021

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“…Examples of novel and recent applications of MCE systems include the use of AC sinusoidal waves, polarity switching, dual‐channel systems, the use of in situ photopolymerized gels, and the addition of sponge‐like materials to the channel liquid reservoirs to function as capillary force suction pumps [595]. In these recent applications, method development included the evaluation and selection of these additional operating conditions.…”

Section: Miniaturization Of Capillary Electrophoresis: Microchip Elec...mentioning

confidence: 99%

Strategies for capillary electrophoresis: Method development and validation for pharmaceutical and biological applications—Updated and completely revised edition

et al. 2023

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This review is in support of the development of selective, precise, fast, and validated capillary electrophoresis (CE) methods. It follows up a similar article from 1998, Wätzig H, Degenhardt M, Kunkel A. “Strategies for capillary electrophoresis: method development and validation for pharmaceutical and biological applications,” pointing out which fundamentals are still valid and at the same time showing the enormous achievements in the last 25 years. The structures of both reviews are widely similar, in order to facilitate their simultaneous use. Focusing on pharmaceutical and biological applications, the successful use of CE is now demonstrated by more than 600 carefully selected references. Many of those are recent reviews; therefore, a significant overview about the field is provided. There are extra sections about sample pretreatment related to CE and microchip CE, and a completely revised section about method development for protein analytes and biomolecules in general. The general strategies for method development are summed up with regard to selectivity, efficiency, precision, analysis time, limit of detection, sample pretreatment requirements, and validation.

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“…Capacitively coupled contactless conductivity detection (C 4 D) has been proved as a promising alternative for the detection of liquid conductivity. [21][22][23][24] Unlike traditional methods, C 4 D allows non-contact analysis of sample conductivity, preventing electrode contamination during detection. This eliminates the need for rigorous cleaning and enables continuous measurements with a simple wipe between tests.…”

Section: Introductionmentioning

confidence: 99%

PCB-C⁴D coupled with paper-based microfluidic sampling for the rapid detection of liquid conductivity

Yang,

Cao,

Zhang

et al. 2024

Anal. Methods

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Capillary and Microchip Electrophoresis

Cited by 6 publications

References 17 publications

LVSEP Analysis of Cationic Analytes in Cationic Polymer-Coating Microchannel Prepared by Vacuum-Drying Method

LVSEP Analysis of Cationic Analytes in Cationic Polymer-Coating Microchannel Prepared by Vacuum-Drying Method

Strategies for capillary electrophoresis: Method development and validation for pharmaceutical and biological applications—Updated and completely revised edition

PCB-C⁴D coupled with paper-based microfluidic sampling for the rapid detection of liquid conductivity

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Capillary and Microchip Electrophoresis

Cited by 6 publications

References 17 publications

LVSEP Analysis of Cationic Analytes in Cationic Polymer-Coating Microchannel Prepared by Vacuum-Drying Method

LVSEP Analysis of Cationic Analytes in Cationic Polymer-Coating Microchannel Prepared by Vacuum-Drying Method

Strategies for capillary electrophoresis: Method development and validation for pharmaceutical and biological applications—Updated and completely revised edition

PCB-C4D coupled with paper-based microfluidic sampling for the rapid detection of liquid conductivity

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PCB-C⁴D coupled with paper-based microfluidic sampling for the rapid detection of liquid conductivity