1994
DOI: 10.1016/0378-4347(94)00092-1
|View full text |Cite
|
Sign up to set email alerts
|

Capillary electrophoresis: separation and quantitation of reverse transcriptase polymerase chain reaction products from polio virus

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

0
5
0
2

Year Published

1998
1998
2017
2017

Publication Types

Select...
7
1

Relationship

0
8

Authors

Journals

citations
Cited by 48 publications
(7 citation statements)
references
References 13 publications
0
5
0
2
Order By: Relevance
“…The model was refined by including 366 datasets from healthy subjects and patients with malignant and nonmalignant genitourinary diseases. In a blinded assessment, the prediction model correctly identified all samples of urothelial carcinoma [sensitivity 100% (95% confidence interval, CI, (87-100)] and all healthy samples [specificity 100% (84)(85)(86)(87)(88)(89)(90)(91)(92)(93)(94)(95)(96)(97)(98)(99)(100)]. The sensitivity of differentiation of urothelial carcinoma from the other malignant and non-malignant genitourinary diseases ranged from 86% to 100%.…”
Section: Urinary Biomarkersmentioning
confidence: 95%
See 1 more Smart Citation
“…The model was refined by including 366 datasets from healthy subjects and patients with malignant and nonmalignant genitourinary diseases. In a blinded assessment, the prediction model correctly identified all samples of urothelial carcinoma [sensitivity 100% (95% confidence interval, CI, (87-100)] and all healthy samples [specificity 100% (84)(85)(86)(87)(88)(89)(90)(91)(92)(93)(94)(95)(96)(97)(98)(99)(100)]. The sensitivity of differentiation of urothelial carcinoma from the other malignant and non-malignant genitourinary diseases ranged from 86% to 100%.…”
Section: Urinary Biomarkersmentioning
confidence: 95%
“…Lu et al [85] performed a quantitative analysis of PCR-amplified HIV-1 DNA or cDNA by CGE with sensitive LIF detection. Other applications include quantification of poliovirus RNA [86], detection of single point mutations [72,87] in Mycobacterium tuberculosis, or separation of indicative PCR products of hepatitis C virus infections [65].…”
Section: Nucleosides Nucleotides Rna and Dnamentioning
confidence: 99%
“…Extraction of nucleic acids is typically performed through a series of organic separations, and has limited applicability to POC testing until with the development of capillary electrophoresis (CE) techniques (Rossomando et al 1994; Woolley et al 1996). These techniques separate migrating samples by trapping them between a leading and trailing buffer in an electrophoretic interphase, while a constant electric field is applied to the channel.…”
Section: Development Of Potential Alternative and Future Biosensors Umentioning
confidence: 99%
“…Die exakte Quantifizierung von PCR-Amplifikaten in biologischen Proben mittels CGE, beispielsweise zur Bestimmung der Genexpression einzelner Proteine, wird durch eine zunehmende Anzahl an Publikationen unterstrichen [140][141][142][143][144]. Außerdem geht'der Trend bei der DNA-Sequenzierung immer mehr in Richtung automatischer Abarbeitung der Proben durch Kapillarelektrophorese [145][146][147][148][149][150][151][152][153][154][155].…”
Section: Molekularbiologische Applikationenunclassified
“…Beispiele aus dem Bereich der molekularbiologischen Infektionsdiagnostik sind der Nachweis von HIV-1 im Blut, [156], Polio-Virus RNA [142], Mycobacterium tuberculosis [157], Hepatitis C DNA-Produkt in humanem Serum [158] oder Cytomegalie-Virus DNA [159]. Im Zusammenhang mit der CGE-Diagnose von Erbkrankheiten [160][161][162][163][164][165][166][167], neoplastischen Erkrankungen [143,[168][169][170] [190].…”
Section: Molekularbiologische Applikationenunclassified