Capsule endoscopy in celiac disease

Spada, Cristiano; Riccioni, Maria Elena; Urgesi, Riccardo; Costamagna, Guido

doi:10.3748/wjg.14.4146

Cited by 51 publications

(35 citation statements)

References 32 publications

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“…CE has a high sensitivity (range, 70%-95.2%), specificity (range, 63.6%-100%) and high PPV and NPV (96.5%-100% and 71.4%-88.9%, respectively) [38,[40][41][42][43] . When an atrophic pattern is detected by CE, the patient has a high probability of having celiac disease [37] . CE has also been reported to be able to demonstrate diseases such as adenocarcinoma, lymphoma or ulcerative jejunoileitis, which may complicate the course of celiac disease.…”

Section: Celiac Diseasementioning

confidence: 99%

“…CE has also been reported to be able to demonstrate diseases such as adenocarcinoma, lymphoma or ulcerative jejunoileitis, which may complicate the course of celiac disease. A limitation is that CE is able to detect Marsh Ⅲ lesions, which are associated with clear mucosal abnormalities, but may not distinguish between Marsh Ⅰ and Ⅱ lesions [37] . At present, CE is an alternative to endoscopy with biopsy in patients with suspected celiac disease who do not consent to the conventional methods.…”

Section: Celiac Diseasementioning

confidence: 99%

“…loss of mucosal folds, mosaic mucosal pattern, scalloping of the duodenal folds and nodularity of the mucosa [37] . It is no surprise that CE provides high resolution images that contain such changes.…”

Section: Celiac Diseasementioning

confidence: 99%

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Five years’ experience with capsule endoscopy in a single center

Kav¹,

Bayraktar²

2009

WJG

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Capsule endoscopy (CE) is a novel technology that facilitates highly effective and noninvasive imaging of the small bowel. Although its efficacy in the evaluation of obscure gastrointestinal bleeding (OGIB) has been proven in several trials, data on uses of CE in different small bowel diseases are rapidly accumulating in the literature, and it has been found to be superior to alternative diagnostic tools in a range of such diseases. Based on literature evidence, CE is recommended as a first-line investigation for OGIB after negative bidirectional endoscopy. CE has gained an important role in the diagnosis and follow-up of Crohn's disease and celiac disease and in the surveillance of small bowel tumors and polyps in selected patients. Capsule retention is the major complication, with a frequency of 1%-2%. The purpose of this review was to discuss the procedure, indications, contraindications and adverse effects associated with CE. We also review and share our five-year experience with CE in various small bowel diseases. The recently developed balloon-assisted enteroscopies have both diagnostic and therapeutic capability. At the present time, CE and balloon-assisted enteroscopies are complementary techniques in the diagnosis and management of small bowel diseases.

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Section: Celiac Diseasementioning

confidence: 99%

Section: Celiac Diseasementioning

confidence: 99%

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Five years’ experience with capsule endoscopy in a single center

Kav¹,

Bayraktar²

2009

WJG

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“…With the increasing spatial resolution now becoming available for videocapsule data acquisition, it will be possible to detect villous atrophy by visual inspection of VCE images (27,28). More macroscopic alterations in the mucosa including scalloping, mosaicism and reduced folds can also be observed in and can be assistive for diagnosis of celiac disease (29).…”

Section: Visual Methodsmentioning

confidence: 99%

Coeliac disease and the videocapsule: what have we learned till now

et al. 2017

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Celiac disease is diagnosed in part by finding areas of pathology in the small bowel (SB) mucosa.This can often be difficult because the pathologic alterations, including atrophy of the small intestinal villi, can often be sparse and subtle. Some of the quantitative methods for detecting and measuring the presence of villous atrophy from videocapsule endoscopy (VCE) images are presented and discussed. These methods consist of static features of measurement including texture, gray level, and presence and abundance of fissures contained within each acquired image. The methods also consist of dynamic measurements including spectral analysis, and determining motion from a sequence of endoscopic images as obtained from a VCE clip. Thus far, several methods have been found useful to characterize the SB mucosa of untreated celiac disease patients versus control patients lacking villous atrophy, which have revealed significant differences in texture, frequency, and motion on analysis of VCE. In untreated celiac patients undergoing endoscopy, there tends to be greater magnitude of changes and spatial differences in textural descriptors, longer periodic components, indicating slower periodic activity, and differences in feature location, suggesting alterations in motility at areas of pathology as compared to patients without villous atrophy. Improvements in the quantitative analysis of VCE imaging in celiac patients is important to detect pathology in suspected patients, so that biopsies can be obtained from pertinent regions of the small intestinal mucosa. Improvements are also necessary so that patients with celiac disease can be monitored to evaluate the progress of mucosal healing after onset of treatment.

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“…In recent issues of this journal we have coordinated the publication of several papers, some covering the latest advances in this field, presenting the use of CE in diagnosis of gastrointestinal bleeding [27] , inflammatory bowel disease [28] , celiac disease [29] , neoplastic disease [30] , non-steroidal anti-inflammatory drugs-enteropathy and rare intestinal diseases [31] , and also its use in pediatric patients [32] . Others studied the value of intestinal preparation before CE [33] , CE use in the colon [34] and esophagus [35] , and the Patency and Agile [36] capsules, and finally another paper was about the future of the CE [37] .…”

Section: Capsule Endoscopymentioning

confidence: 99%