Capsule Endoscopy Is Superior to Small-bowel Follow-through and Equivalent to Ileocolonoscopy in Suspected Crohn's Disease

Leighton, Jonathan A.; Gralnek, Ian M.; Cohen, Stanley A.; Tóth, Ervin; Cave, David R.; Wolf, Douglas C.; Mullin, Gerard E.; Ketover, Scott R.; Legnani, Peter; Seidman, Ernest G.; Crowell, Michael D.; Bergwerk, Ari; Peled, Ravit; Eliakim, Rami

doi:10.1016/j.cgh.2013.09.028

Cited by 55 publications

(39 citation statements)

References 15 publications

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“…VCE can be useful in the management of patients with known[35,36] or suspected IBD[37], by visualising mucosa not readily accessible by standard endoscopy. VCE is generally safe in patients with CD[35], the main complication of VCE is that of capsule retention.…”

Section: Capsule Endoscopymentioning

confidence: 99%

“…A prospective, multi-centered, blinded cohort study of patients with suspected CD found that VCE is equivalent to ileo-colonoscopy in detecting ileo-caecal inflammation, and is superior to small bowel follow through studies[37]. In patients with suspected inflammatory phenotype CD, VCE is safe and can confirm diagnosis of CD in the presence of a normal ileo-colonoscopy[37].…”

Section: Capsule Endoscopymentioning

confidence: 99%

“…In patients with suspected inflammatory phenotype CD, VCE is safe and can confirm diagnosis of CD in the presence of a normal ileo-colonoscopy[37]. VCE was superior to MRE and CTE in detecting mucosal lesions proximal to the terminal ileum, in a blinded prospective study of patients with suspected or newly diagnosed CD[39].…”

Section: Capsule Endoscopymentioning

confidence: 99%

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Endoscopic evaluation in diagnosis and management of inflammatory bowel disease

Moran

Neary

Doherty

2016

WJGE

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Endoscopy is a keystone in the management of patients with inflammatory bowel disease (IBD). It is the fundamental diagnostic tool for IBD, and can help discern between ulcerative colitis and Crohn’s disease. Endoscopic assessment provides an objective end point in clinical trials, and identifies patients in clinical practice who may benefit from treatment escalation and may assist risk stratification in patients seeking to discontinue therapy. Recent advances in endoscopic assessment of patients with IBD include video capsule endoscopy, and chromoendoscopy. Technological advances enable improved visualization and focused biopsy sampling. Endoscopic resection and close surveillance of dysplastic lesions where feasible is recommended instead of prophylactic colectomy.

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Section: Capsule Endoscopymentioning

confidence: 99%

Section: Capsule Endoscopymentioning

confidence: 99%

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Endoscopic evaluation in diagnosis and management of inflammatory bowel disease

Moran

Neary

Doherty

2016

WJGE

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“…Initial studies supported the wide use of SBCE in the investigation of suspected small bowel CD with normal ileocolonoscopy (IC) by reporting diagnostic superiority [12][13][14] and significant diagnostic yield compared with other modalities [15][16][17][18][19]. The main drawbacks of the oldgeneration capsules were their limited battery life, with up to 25% of them not reaching the colon during recording, a disadvantage that is almost eliminated with the development of capsules with a longer battery life, namely, EndoCapsule 10, MiroCam, Pillcam SB2-ex [20,21] and SB3, as well as the fear of capsule retention.…”

Section: Introductionmentioning

confidence: 96%

The role of small bowel capsule endoscopy and ileocolonoscopy in patients with nonspecific but suggestive symptoms of Crohn’s disease

Mitselos

Christodoulou

Κατσάνος

et al. 2016

European Journal of Gastroenterology &Amp; Hepatology

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“…42 SBCE has a high sensitivity for lesions consistent with small bowel CD, including mild lesions and those located in the proximal small bowel. [43][44][45] In patients with suspected CD, it is possible to confidently exclude the diagnosis when no lesions are identified by SBCE 46 . However, the lesions which are typical of active small bowel CD, such as villous oedema or aphthous ulcerations (Fig.…”

Section: Crohn's Diseasementioning

confidence: 99%

Current Clinical Indications for Small Bowel Capsule Endoscopy

Rosa

Cotter

2015

Acta Med Port

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RESUMOIntrodução: A enteroscopia por cápsula é o exame de primeira linha no diagnóstico de diversas patologias do intestino delgado. Este artigo tem por objectivo rever e analisar criticamente as indicações actuais para enteroscopia por cápsula na prática clínica. Material e Métodos: Revisão bibliográfica suportada em artigos indexados na PubMed. Resultados e Discussão: A enteroscopia por cápsula permite a avaliação não invasiva da mucosa do intestino delgado, com elevado rendimento diagnóstico. Em doentes com hemorragia digestiva de causa obscura, o rendimento da enteroscopia por cápsula aumenta quando realizada precocemente após o evento hemorrágico. O tratamento das angiectasias com enteroscopia assistida por balão permite diminuir a recidiva hemorrágica, enquanto o risco de recidiva em doentes com enteroscopia por cápsula "negativa" é controverso. A entero-TC/entero-RM podem superiorizar-se à enteroscopia por cápsula no diagnóstico de alguns tumores. O 'Smooth Protruding Index on Capsule Endoscopy' (score SPICE) auxilia na diferenciação entre verdadeiros tumores submucosos e abaulamentos não patológicos. A enteroscopia por cápsula é valiosa em doentes com suspeita de doença de Crohn quando a ileocolonoscopia não é diagnóstica, permitindo também estadiar a extensão e actividade das lesões em doentes com diagnóstico prévio de doença de Crohn, com potenciais implicações prognósticas e terapêuticas. A enteroscopia por cápsula permite ainda o diagnóstico de complicações em doentes com doença celíaca refractária. Conclusões: Actualmente, a importância da enteroscopia por cápsula é reconhecida no contexto da hemorragia digestiva de causa obscura e/ou suspeita de tumores do intestino delgado, bem como na suspeita de doença de Crohn ou em doentes com doença de Crohn conhecida para determinar a localização, extensão e actividade da doença, e ainda para a investigação de doentes com doença celíaca refractária. Palavras-chave: Doenças Intestinais; Endoscopia por Cápsula. ABSTRACT Introduction:Small bowel capsule endoscopy is currently the first line diagnostic examination for many diseases affecting the small bowel. This article aims to review and critically address the current indications of small bowel capsule endoscopy in clinical practice. Material and Methods: Bibliographic review of relevant and recent papers indexed in PubMed.

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Capsule Endoscopy Is Superior to Small-bowel Follow-through and Equivalent to Ileocolonoscopy in Suspected Crohn's Disease

Cited by 55 publications

References 15 publications

Endoscopic evaluation in diagnosis and management of inflammatory bowel disease

Endoscopic evaluation in diagnosis and management of inflammatory bowel disease

The role of small bowel capsule endoscopy and ileocolonoscopy in patients with nonspecific but suggestive symptoms of Crohn’s disease

Current Clinical Indications for Small Bowel Capsule Endoscopy

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