Capture and sorting of multiple cells by polarization-controlled three-beam interference

Hou, Yu; Wang, Zuobin; Hu, Ying; Li, Dayou; Qiu, Renxi

doi:10.1088/2040-8978/18/3/035401

Cited by 6 publications

(5 citation statements)

References 17 publications

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“…Equation (8) shows that for different azimuth and incident angles, we need to choose different beam polarization modes to maximize the contrast of the interference field. Owing to the incident surfaces of the two light waves not being coplanar, there is no case where the horizontal polarization component is totally in the same direction.…”

Section: Contrast In Double-beam Non-coplanar Interference Patternsmentioning

confidence: 99%

“…This condition is verified in Figure 2. We simulated the contrast of all linear polarization orientations when the azimuth angles were 30°, 60°, 90°, 120°, 150°and 180°, and Equation (8) shows that for different azimuth and incident angles, we need to choose different beam polarization modes to maximize the contrast of the interference field.…”

Section: Contrast In Double-beam Non-coplanar Interference Patternsmentioning

confidence: 99%

“…LIL was first used to fabricate one-dimensional (1D) grating using double-beam interference. With the addition of a third or further beams, 2D and 3D lattice interference patterns can be generated, including all 2D and 3D Bravais lattice structures [7][8][9][10][11].…”

Section: Introductionmentioning

confidence: 99%

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Contrast Analysis of Polarization in Three-Beam Interference Lithography

Peng

et al. 2021

Applied Sciences

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This paper analyzes the effect of polarization and the incident angle on the contrasts of interference patterns in three-beam interference lithography. A non-coplanar laser interference system was set up to simulate the relationship between contrast, beam polarization, and the incident angle. Different pattern periods require different incident angles, which means different contrast losses in interference lithography. Two different polarization modes were presented to study the effects of polarization with different incident angles based on theoretical analysis simulations. In the case of the co-directional component TE polarization mode, it was demonstrated that the pattern contrast decreases with the increase in the incident angle and the contrast loss caused by the polarization angle error also grew rapidly. By changing the mode to azimuthal (TE-TE-TE) polarization, the contrast of the interference pattern can be ensured to remain above 0.97 even though the incident angle is large. In addition, TE-TE-TE mode can accept larger polarization angle errors. This conclusion provides a theoretical basis for the generation of high-contrast light fields at different incident angles, and the conclusion is also applicable to multi-beam interference lithography.

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Section: Contrast In Double-beam Non-coplanar Interference Patternsmentioning

confidence: 99%

Section: Contrast In Double-beam Non-coplanar Interference Patternsmentioning

confidence: 99%

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Contrast Analysis of Polarization in Three-Beam Interference Lithography

Peng

et al. 2021

Applied Sciences

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“…Diffential interference phase contrast microscopy using multiple beam shearing interferometry for bio-imaging was applied in 2006(Roy et al, 2006. Capturing and sorting of multiple cells by polarization-controlled three-beam interference was realized in 2016 (Hou et al, 2016). But such methods were not applied for carcinoma cells.…”

Section: Why Interference Microscopy Is Optimal Micro-technique For Amentioning

confidence: 99%

Multi-Beam Interference Patterns of Living Sarcoma Cells may be Approximated by a Fractal Julia Set and Rieman Spheres or Fatou Components Decoded as a Siegel Discs

2019

European Journal of Medicine

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It's well known, that the morphology of a carcinoma cells was studied many a time and oft (on repeated occasions) from the second part of the XX century. But mathematical approximations of such sarcoma cell structures are not very good on the grounds of non-regular semi-chaotic elements in morphogenesis and morphology of cancer cells. Many approximations in sarcoma oncology works are not applying for cell morphology as is, despite the fact of good morphological representation of sarcoma cells in different microscopic and specific-staining methods. Our work is a first work where the multi-beam interference patterns of living sarcoma cells are approximated by a fractal Julia set and Fatou components known as a Siegel discs.

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“…When a laser beam is focused on a particle or cell, it forms a three dimensional optical potential well that can induce optical pressure to capture particle. The captured particles or cells can be transported for sorting [81][82][83][84] or patterning 85,86 by controlling the track of optical tweezers. The sorting methods based on optical tweezers can be classified into passive and active modes.…”

Section: Optical Tweezersmentioning

confidence: 99%

Microfluidics cell sample preparation for analysis: Advances in efficient cell enrichment and precise single cell capture

et al. 2017

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Single cell analysis has received increasing attention recently in both academia and clinics, and there is an urgent need for effective upstream cell sample preparation. Two extremely challenging tasks in cell sample preparation-highefficiency cell enrichment and precise single cell capture-have now entered into an era full of exciting technological advances, which are mostly enabled by microfluidics. In this review, we summarize the category of technologies that provide new solutions and creative insights into the two tasks of cell manipulation, with a focus on the latest development in the recent five years by highlighting the representative works. By doing so, we aim both to outline the framework and to showcase example applications of each task. In most cases for cell enrichment, we take circulating tumor cells (CTCs) as the target cells because of their research and clinical importance in cancer. For single cell capture, we review related technologies for many kinds of target cells because the technologies are supposed to be more universal to all cells rather than CTCs. Most of the mentioned technologies can be used for both cell enrichment and precise single cell capture. Each technology has its own advantages and specific challenges, which provide opportunities for researchers in their own area. Overall, these technologies have shown great promise and now evolve into real clinical applications. Published by AIP Publishing. [http://dx

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Capture and sorting of multiple cells by polarization-controlled three-beam interference

Cited by 6 publications

References 17 publications

Contrast Analysis of Polarization in Three-Beam Interference Lithography

Contrast Analysis of Polarization in Three-Beam Interference Lithography

Multi-Beam Interference Patterns of Living Sarcoma Cells may be Approximated by a Fractal Julia Set and Rieman Spheres or Fatou Components Decoded as a Siegel Discs

Microfluidics cell sample preparation for analysis: Advances in efficient cell enrichment and precise single cell capture

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