“…Carbamazepine (CBZ) is a major antiepileptic agent and its clinical efficacy has been stressed by several authors (Cereghino, Brock, van Meter, Penry, Smith & White, 1974;Dalby, 1971;Monaco, Riccio, Benna, Covacich, Durelli, Fantini, Furlan, Gilli, Mutani, Troni, Gerna & Morselli, 1976;Rodin, Rim & Rennick, 1974;Troupin, Green & Levy, 1974). The pharmacokinetics and the metabolism of the drug have been extensively described in both experimental animals and man (Farghali-Hassan, Assael, Bossi, Gerna, Garattini, Gomeni & Morselli, 1976;Levy, Lockard, Green, Friel & Martis, 1975;Levy Pitlick, Troupin, Green & Neal, 1975;Morselli, 1975;Morselli, Gerna & Garattini, 1971;.…”