Carbohydrates

Khan, Mukhtar I.

doi:10.1016/b978-1-4377-0974-2.00016-6

Cited by 14 publications

(8 citation statements)

References 138 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…THSG extracted from HSW has been shown to have hypoglycemic effects and to protect against nephropathy in mice and rats (Li et al, 2010; Chen et al, 2016; Zhang et al, 2012). HbA 1c levels reflect average blood glucose levels over the past 2~3 months (Khan and Weinstock, 2011); we therefore measured HbA 1c levels in the present study. Although not statistically significant, HSW-administered mice showed a decrease in HbA 1c levels approximately 10.4% (Fig.…”

Section: Resultsmentioning

confidence: 99%

Heshouwu (Polygonum multiflorum Thunb.) Extract Attenuates Bone Loss in Diabetic Mice

Ham¹,

Lee²,

Choi³

et al. 2019

pnf

View full text Add to dashboard Cite

This study investigated the effects and mechanism of Heshouwu (Polygonum multiflorum Thunb.) water extract (HSW) on diabetes-related bone loss in mice. HSW was orally administered (300 mg/kg body weight) to high-fat diet and streptozotocin-induced diabetic mice for 10 weeks. HSW significantly alleviated mouse body weight loss and hyperglycemia compared with the control group, and elevated serum levels of insulin, osteocalcin, and bone-alkaline phosphatase. HSW supplementation also significantly increased the bone volume/tissue volume ratio and trabecular thickness and number, and decreased the bone surface/bone volume ratio and trabecular structure model index in the femur and tibia. Moreover, HSW significantly increased femoral bone mineral density. In addition, HSW down-regulated osteoclastogenic genes, such as nuclear factor of activated T-cells, cytoplasmic 1 and tartrate-resistant acid phosphatase 5 (TRAP), in both the femur and tibia tissue, and reduced serum TRAP level compare to those of control mice. These results indicate that HSW might relieve diabetes-related bone disorders through regulating osteoclast-related genes, suggesting HSW may be used as a preventive agent for diabetes-induced bone loss.

show abstract

Section: Resultsmentioning

confidence: 99%

Heshouwu (Polygonum multiflorum Thunb.) Extract Attenuates Bone Loss in Diabetic Mice

Ham¹,

Lee²,

Choi³

et al. 2019

pnf

View full text Add to dashboard Cite

show abstract

“…The intervention will be delivered over 6 months to allow sufficient time for dietary changes to be reflected in approximately two A1C cycles. 97 …”

Section: Interventionmentioning

confidence: 99%

“…A household member is defined as a partner or a dependent child or adult who resides at the same location at least 50% of the time. The intervention will be delivered over 6 months to allow sufficient time for dietary changes to be reflected in approximately two A1C cycles 97…”

Section: Interventionmentioning

confidence: 99%

Healthy food prescription incentive programme for adults with type 2 diabetes who are experiencing food insecurity: protocol for a randomised controlled trial, modelling and implementation studies

et al. 2022

View full text Add to dashboard Cite

IntroductionThe high cost of many healthy foods poses a challenge to maintaining optimal blood glucose levels for adults with type 2 diabetes mellitus who are experiencing food insecurity, leading to diabetes complications and excess acute care usage and costs. Healthy food prescription programmes may reduce food insecurity and support patients to improve their diet quality, prevent diabetes complications and avoid acute care use. We will use a type 2 hybrid-effectiveness design to examine the reach, effectiveness, adoption, implementation and maintenance (RE-AIM) of a healthy food prescription incentive programme for adults experiencing food insecurity and persistent hyperglycaemia. A randomised controlled trial (RCT) will investigate programme effectiveness via impact on glycosylated haemoglobin (primary outcome), food insecurity, diet quality and other clinical and patient-reported outcomes. A modelling study will estimate longer-term programme effectiveness in reducing diabetes-related complications, resource use and costs. An implementation study will examine all RE-AIM domains to understand determinants of effective implementation and reasons behind programme successes and failures.Methods and analysis594 adults who are experiencing food insecurity and persistent hyperglycaemia will be randomised to a healthy food prescription incentive (n=297) or a healthy food prescription comparison group (n=297). Both groups will receive a healthy food prescription. The incentive group will additionally receive a weekly incentive (CDN$10.50/household member) to purchase healthy foods in supermarkets for 6 months. Outcomes will be assessed at baseline and follow-up (6 months) in the RCT and analysed using mixed-effects regression. Longer-term outcomes will be modelled using the UK Prospective Diabetes Study outcomes simulation model-2. Implementation processes and outcomes will be continuously measured via quantitative and qualitative data.Ethics and disseminationEthical approval was obtained from the University of Calgary and the University of Alberta. Findings will be disseminated through reports, lay summaries, policy briefs, academic publications and conference presentations.Trial registration numberNCT04725630.Protocol versionVersion 1.1; February 2022

show abstract

“…As the average amount of plasma glucose increases, the fraction of glycated hemoglobin increases in a predictable way. This serves as a marker for average blood glucose levels over the previous 3 months before the measurement as this is the lifespan of red blood cells [2][3].…”

Section: Introductionmentioning

confidence: 99%

Assessment of Cumulative Glycated Hemoglobin in Children and Adolescents with Type 1 Diabetes in Alzawia Diabetic Patients

Alzubidy,

Alrawi

2023

Cross Current Int J Med Biosci

View full text Add to dashboard Cite

As a result of the pancreas not secreting the hormone insulin or secreting it in a low concentration, as the hormone is important in enhancing the ability of glucose to enter cells and produce energy, and the cumulative glucose analysis is HbA1c, also known as glycated hemoglobin, which is a product of glucose adhesion in the body with red blood cells (RBC). The pellets are effective from two to three months, and for this reason, 3 cumulative glucose readings are taken for the same period. This study was conducted at Al-Zawiya Central Hospital, Children’s Department, for 100 children with type 1 diabetes, of whom 46 were males and 54 were females, the purpose of this study is to evaluate the cumulative sugar levels for children and adolescents with diabetes, as the study showed a weakness in the cumulative rate, which was high at a rate of 10.6%, and a lack of care for diabetes with a lack of regular exercise.

show abstract

Carbohydrates

Cited by 14 publications

References 138 publications

Heshouwu (Polygonum multiflorum Thunb.) Extract Attenuates Bone Loss in Diabetic Mice

Heshouwu (Polygonum multiflorum Thunb.) Extract Attenuates Bone Loss in Diabetic Mice

Healthy food prescription incentive programme for adults with type 2 diabetes who are experiencing food insecurity: protocol for a randomised controlled trial, modelling and implementation studies

Assessment of Cumulative Glycated Hemoglobin in Children and Adolescents with Type 1 Diabetes in Alzawia Diabetic Patients

Contact Info

Product

Resources

About