Carbon-dot–hydrogel for enzyme-mediated bacterial detection

Bhattacharya, Sagarika; Nandi, Sukhendu; Jelinek, Raz

doi:10.1039/c6ra25148j

Cited by 57 publications

(50 citation statements)

References 50 publications

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“…In recent years, hydrogels have been receiving considerable attention due to their variety of applications, such as drug delivery, biomedical, tissue engineering, in vitro, and related to in vivo requirements . The hydrogels are mainly two types, weak and strong gels .…”

Section: Introductionmentioning

confidence: 99%

“…The hydrogels are mainly two types, weak and strong gels . However, weak gels have certain advantage of self‐healing over strong gels and others gel ,,,. According to recent reports, fluorescent CD‐hybrids gel exhibit improved mechanical strength and thermal stability compared to bare gel for their applications in detection of bacteria and in the sensing of different metal ions .…”

Section: Introductionmentioning

confidence: 99%

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Green Synthesis of Carbon Dot Weak Gel from Pear Juice: Optical Properties and Sensing Application

Mondal

Srivastava

2018

ChemistrySelect

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Herein, we report for the first time a low-cost and eco-friendly carbon dot weak gel (CDWG) in the absence of any gelling agent from a pear juice as a green precursor. Our findings showed that the volatile nature of acetone, basic media, and cellulose content in pear juice played key roles in the formation of CDWG. This fabrication strategy of CDWG from a green precursor in absence of gelling agent could be more advantageous over CD-hybrids gel. Further, the fabricated gel exhibited excitation dependent red shifted multicolor (blue-green-yellow-orange) emission due to the presence of characteristic hydrophilic surface in CDs. The other unique feature of the work involved utilization of inherent fluorescent property of CDs in establishing optical interaction between 0D CDWG and 2D reduced graphene oxide (G) and graphene oxide (GO). It may be concluded that the quenching is mainly guided by the electron rich CDs and electron acceptance ability, large specific surface area of G and GO. It is also interesting to note that the introducing of gel property in CDs exhibit improved sensing efficiency and limit of detection of CDWG (1.5 μg ml À 1 ) for G. Further, such optical sensing could be beneficial for the fabrication of optoelectronics, photovoltaic devices and sensing of bio-molecules and metal ions.[a] J.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Green Synthesis of Carbon Dot Weak Gel from Pear Juice: Optical Properties and Sensing Application

Mondal

Srivastava

2018

ChemistrySelect

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“…For instance, Bhattacharya et al loaded fluorescent carbon dots within a hydrogel prepared from 6-O-(O-O -dilauroyltartaryl)-d-glucose, for an esterase-based gel cleavage and detection of several bacteria like Bacillus cereus, Staphylococcus aureus, and Bacillus subtilis. Here, the bacterially secreted esterase results in the fluidization of the hydrogel, aggregation of the embedded carbon dots, and consequently their discernable quenching [135]. in which fluorescence recovery occurred selectively upon contacting cytotoxic virulence factors secreted by wound pathogens.…”

Section: Bacterial Infectionsmentioning

confidence: 99%

Hydrogel-Based Technologies for the Diagnosis of Skin Pathology

et al. 2020

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Hydrogels, swellable hydrophilic polymer networks fabricated through chemical cross-linking or physical entanglement are increasingly utilized in various biomedical applications over the past few decades. Hydrogel-based microparticles, dressings and microneedle patches have been explored to achieve safe, sustained and on-demand therapeutic purposes toward numerous skin pathologies, through incorporation of stimuli-responsive moieties and therapeutic agents. More recently, these platforms are expanded to fulfill the diagnostic and monitoring role. Herein, the development of hydrogel technology to achieve diagnosis and monitoring of pathological skin conditions are highlighted, with proteins, nucleic acids, metabolites, and reactive species employed as target biomarkers, among others. The scope of this review includes the characteristics of hydrogel materials, its fabrication procedures, examples of diagnostic studies, as well as discussion pertaining clinical translation of hydrogel systems.

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“…To achieve more remarkable performance, CDs are usually modied to couple with other materials, such as metal and nonmetal nanoparticles, [17][18][19][20][21][22] as well as organic and polymeric materials. [23][24][25][26][27][28][29][30] Shi et al synthesized core-shell Au@CDs NPs with a shell CD-thickness of ca. 2 nm through the direct reduction of HAuCl 4 by CDs, which enhanced surface Raman scattering measurements.…”

Section: Introductionmentioning

confidence: 99%